ENSG00000167178


Homo sapiens

Features
Gene ID: ENSG00000167178
  
Biological name :ISLR2
  
Synonyms : immunoglobulin superfamily containing leucine rich repeat 2 / ISLR2 / Q6UXK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q24.1
Gene start: 74100311
Gene end: 74138540
  
Corresponding Affymetrix probe sets: 232208_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458080
Ensembl peptide - ENSP00000455076
Ensembl peptide - ENSP00000455531
Ensembl peptide - ENSP00000355402
Ensembl peptide - ENSP00000408872
Ensembl peptide - ENSP00000411443
Ensembl peptide - ENSP00000411834
Ensembl peptide - ENSP00000454259
Ensembl peptide - ENSP00000454287
Ensembl peptide - ENSP00000454859
NCBI entrez gene - 57611     See in Manteia.
OMIM - 614179
RefSeq - XM_017022446
RefSeq - NM_001130136
RefSeq - NM_001130137
RefSeq - NM_001130138
RefSeq - NM_020851
RefSeq - XM_011521840
RefSeq - XM_011521841
RefSeq Peptide - NP_065902
RefSeq Peptide - NP_001123609
RefSeq Peptide - NP_001123610
RefSeq Peptide - NP_001123608
swissprot - Q6UXK2
swissprot - H3BM69
swissprot - H3BM95
swissprot - H3BNZ6
swissprot - Q24JQ5
Ensembl - ENSG00000167178
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 islr2ENSDARG00000051875Danio rerio
 ENSGALG00000021525Gallus gallus
 ISLR2ENSGALG00000029151Gallus gallus
 Islr2ENSMUSG00000051243Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ISLR / O14498 / immunoglobulin superfamily containing leucine rich repeatENSG0000012900929
LRIT3 / Q3SXY7 / leucine rich repeat, Ig-like and transmembrane domains 3ENSG0000018342319
LRIT1 / Q9P2V4 / leucine rich repeat, Ig-like and transmembrane domains 1ENSG0000014860217
LRIT2 / A6NDA9 / leucine rich repeat, Ig-like and transmembrane domains 2ENSG0000020403315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0045773 positive regulation of axon extension IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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