ENSG00000153130


Homo sapiens
proteinSCOCregulationgolgimembraneshortcoiled-coilmacroautophagycomplexstabilitynucleoplasmcytoplasmendosomeapparatustrans-golginetworkcytosolbindingretrogradetransporttrans-golgi-network

Features
Gene ID: ENSG00000153130
  
Biological name :SCOC
  
Synonyms : Q9UIL1 / SCOC / short coiled-coil protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q31.1
Gene start: 140257286
Gene end: 140385726
  
Corresponding Affymetrix probe sets: 223341_s_at (Human Genome U133 Plus 2.0 Array)   224786_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477352
Ensembl peptide - ENSP00000477812
Ensembl peptide - ENSP00000345262
Ensembl peptide - ENSP00000377751
Ensembl peptide - ENSP00000377753
Ensembl peptide - ENSP00000377755
Ensembl peptide - ENSP00000421355
Ensembl peptide - ENSP00000424605
Ensembl peptide - ENSP00000424688
Ensembl peptide - ENSP00000426649
Ensembl peptide - ENSP00000426810
NCBI entrez gene - 60592     See in Manteia.
RefSeq - NM_001153552
RefSeq - NM_001153446
RefSeq - NM_001153484
RefSeq - NM_001153585
RefSeq - NM_001153635
RefSeq - NM_001153663
RefSeq - NM_001153690
RefSeq - NM_032547
RefSeq Peptide - NP_001147162
RefSeq Peptide - NP_115936
RefSeq Peptide - NP_001146956
RefSeq Peptide - NP_001147024
RefSeq Peptide - NP_001147057
RefSeq Peptide - NP_001146918
RefSeq Peptide - NP_001147107
RefSeq Peptide - NP_001147135
swissprot - A0A0C4DGB0
swissprot - Q9UIL1
Ensembl - ENSG00000153130
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scocaENSDARG00000087333Danio rerio
 scocbENSDARG00000002217Danio rerio
 SCOCENSGALG00000009813Gallus gallus
 ScocENSMUSG00000063253Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019357  Short coiled-coil protein


Gene Ontology (GO)
catabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcellular metabolic processprocess utilizing autophagic mechanismregulation of biological qualitycatabolic processcatabolic processcellular metabolic processcellular metabolic processprocess utilizing autophagic mechanprocess utilizing autophagic mechanismregulation of biological qualityregulation of biological quality
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellmembraneorganellemembrane-enclosed lumencellcellmembranemembraneorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0016239 positive regulation of macroautophagy IDA
 biological_processGO:0061635 regulation of protein complex stability IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000120805 ARL1 / P40616 / ADP ribosylation factor like GTPase 1  / complex / reaction






 

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