ENSGALG00000001366


Gallus gallus

Features
Gene ID: ENSGALG00000001366
  
Biological name :CASP9
  
Synonyms : CASP9 / caspase 9
  
Possible biological names infered from orthology : Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA. / P55211 / Q8C3Q9
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 4917508
Gene end: 4923271
  
Corresponding Affymetrix probe sets: Gga.4116.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002083
NCBI entrez gene - 426970     See in Manteia.
RefSeq - XM_424580
swissprot - F1NL59
Ensembl - ENSGALG00000001366
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casp9ENSDARG00000004325Danio rerio
 CASP9ENSG00000132906Homo sapiens
 Casp9ENSMUSG00000028914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*ENSGALG0000001469826
CASP8 / caspase-8 / O89110* / Q14790* / Caspase-8 Caspase-8 subunit p18 Caspase-8 subunit p10*ENSGALG0000000835524
CASP10 / caspase 10 / Q92851*ENSGALG0000004649424
CASP7 / caspase 7 / P55210* / P97864* / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11*ENSGALG0000000893323
CASP18ENSGALG0000000834622
CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*ENSGALG0000001063822
CASP6 / caspase-6 / O08738* / P55212* / Caspase-6 Caspase-6 subunit p18 Caspase-6 subunit p11*ENSGALG0000001218621


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR001315  CARD domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR011029  Death-like domain superfamily
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR016129  Peptidase family C14A, His active site
 IPR029030  Caspase-like domain superfamily
 IPR033139  Peptidase family C14A, cysteine active site
 IPR033171  Caspase-9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0042770 signal transduction in response to DNA damage IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0060561 apoptotic process involved in morphogenesis IDA
 biological_processGO:0070306 lens fiber cell differentiation IDA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0097194 execution phase of apoptosis IBA
 biological_processGO:2001020 regulation of response to DNA damage stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043293 apoptosome IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
Formation of apoptosome
Activation of caspases through apoptosome-mediated cleavage
NOD1/2 Signaling Pathway
AKT phosphorylates targets in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001366 CASP9 / caspase 9 / P55211* / Q8C3Q9* / Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA.*  / complex
 ENSGALG00000008933 CASP7 / caspase 7 / P55210* / P97864* / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11*  / reaction
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction
 ENSGALG00000011020 CYCS / P67881 / Cytochrome c / P99999* / P62897* / Gm10053* / predicted gene 10053* / cytochrome c, somatic*  / complex / reaction
 ENSGALG00000011531 APAF1 / apoptotic peptidase activating factor 1 / O14727* / O88879* / Apoptotic protease-activating factor 1 *  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr