ENSGALG00000005086


Gallus gallus

Features
Gene ID: ENSGALG00000005086
  
Biological name :PLAU
  
Synonyms : plasminogen activator, urokinase / PLAU
  
Possible biological names infered from orthology : P00749 / P06869
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 15493644
Gene end: 15501817
  
Corresponding Affymetrix probe sets: Gga.19715.1.A1_at (Chicken Array)   Gga.19715.1.S1_at (Chicken Array)   Gga.817.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008143
NCBI entrez gene - 396424     See in Manteia.
RefSeq - NM_205443
RefSeq Peptide - NP_990774
swissprot - F1NYX5
Ensembl - ENSGALG00000005086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plauaENSDARG00000075265Danio rerio
 plaubENSDARG00000039145Danio rerio
 PLAUENSG00000122861Homo sapiens
 PlauENSMUSG00000021822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLAT / plasminogen activator, tissue type / P00750* / P11214* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B*ENSGALG0000000370938
HGFAC / HGF activator / Q04756* / Q9R098* / hepatocyte growth factor activator*ENSGALG0000001562335
HABP2 / hyaluronan-binding protein 2 preproprotein / Q14520* / hyaluronan binding protein 2* / Mus musculus hyaluronic acid binding protein 2 (Habp2), transcript variant 1, mRNA.*ENSGALG0000000890533
LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*ENSGALG0000000429330
F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*ENSGALG0000000833225
LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*ENSGALG0000002888625
MST1 / hepatocyte growth factor-like protein precursor / P26928* / macrophage stimulating 1* / macrophage stimulating 1 (hepatocyte growth factor-like)*ENSGALG0000000272224
HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*ENSGALG0000003397423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000742  EGF-like domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR013032  EGF-like, conserved site
 IPR013806  Kringle-like fold
 IPR018056  Kringle, conserved site
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014909 smooth muscle cell migration IEA
 biological_processGO:0014910 regulation of smooth muscle cell migration IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031639 plasminogen activation IEA
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042730 fibrinolysis IEA
 biological_processGO:2000097 regulation of smooth muscle cell-matrix adhesion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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