ENSGALG00000015623


Gallus gallus

Features
Gene ID: ENSGALG00000015623
  
Biological name :HGFAC
  
Synonyms : HGFAC / HGF activator
  
Possible biological names infered from orthology : hepatocyte growth factor activator / Q04756 / Q9R098
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 82506600
Gene end: 82546305
  
Corresponding Affymetrix probe sets: GgaAffx.9956.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025139
NCBI entrez gene - 422876     See in Manteia.
RefSeq - XM_420819
swissprot - E1BZN8
Ensembl - ENSGALG00000015623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HGFACENSG00000109758Homo sapiens
 HgfacENSMUSG00000029102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*ENSGALG0000000429331
HABP2 / hyaluronan-binding protein 2 preproprotein / Q14520* / hyaluronan binding protein 2* / Mus musculus hyaluronic acid binding protein 2 (Habp2), transcript variant 1, mRNA.*ENSGALG0000000890530
PLAT / plasminogen activator, tissue type / P00750* / P11214* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B*ENSGALG0000000370929
PLAU / plasminogen activator, urokinase / P00749* / P06869*ENSGALG0000000508626
MST1 / hepatocyte growth factor-like protein precursor / P26928* / macrophage stimulating 1* / macrophage stimulating 1 (hepatocyte growth factor-like)*ENSGALG0000000272225
LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*ENSGALG0000002888625
F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*ENSGALG0000000833223
HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*ENSGALG0000003397422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000001  Kringle
 IPR000083  Fibronectin, type I
 IPR000562  Fibronectin type II domain
 IPR000742  EGF-like domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR013032  EGF-like, conserved site
 IPR013806  Kringle-like fold
 IPR018056  Kringle, conserved site
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
MET Receptor Activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015623 HGFAC / HGF activator / Q04756* / Q9R098* / hepatocyte growth factor activator*  / complex
 ENSGALG00000033974 HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction






 

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