ENSGALG00000005698


Gallus gallus

Features
Gene ID: ENSGALG00000005698
  
Biological name :HIF1AN
  
Synonyms : HIF1AN / hypoxia inducible factor 1 alpha subunit inhibitor
  
Possible biological names infered from orthology : Hypoxia-inducible factor 1-alpha inhibitor / Q8BLR9 / Q9NWT6
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 17408516
Gene end: 17416044
  
Corresponding Affymetrix probe sets: Gga.7739.1.S1_at (Chicken Array)   GgaAffx.3569.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009127
NCBI entrez gene - 428952     See in Manteia.
RefSeq - XM_426507
swissprot - F1N863
Ensembl - ENSGALG00000005698
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hif1anENSDARG00000031915Danio rerio
 HIF1ANENSG00000166135Homo sapiens
 Hif1anENSMUSG00000036450Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPBAP1 / HSPB1 associated protein 1 / Q8BK58* / Q96EW2*ENSGALG0000001167723
KDM8 / lysine demethylase 8 / Q8N371* / Q9CXT6* / JmjC domain-containing protein 5 *ENSGALG0000000630121
TYW5 / E1C7T6 / tRNA wybutosine-synthesizing protein 5 / A2RUC4* / A2RSX7* / tRNA-yW synthesizing protein 5*ENSGALG0000000814518


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain
 IPR027445  Hypoxia-inducible factor 1-alpha inhibitor
 IPR027452  Hypoxia-inducible factor 1-alpha inhibitor, domain II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0036138 peptidyl-histidine hydroxylation IEA
 biological_processGO:0042264 peptidyl-aspartic acid hydroxylation IEA
 biological_processGO:0042265 peptidyl-asparagine hydroxylation IEA
 biological_processGO:0045663 positive regulation of myoblast differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005112 Notch binding IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0031406 carboxylic acid binding IEA
 molecular_functionGO:0036139 peptidyl-histidine dioxygenase activity IEA
 molecular_functionGO:0036140 peptidyl-asparagine 3-dioxygenase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0048037 cofactor binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA
 molecular_functionGO:0071532 ankyrin repeat binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005698 HIF1AN / hypoxia inducible factor 1 alpha subunit inhibitor / Q8BLR9* / Q9NWT6* / Hypoxia-inducible factor 1-alpha inhibitor *  / complex
 ENSGALG00000010005 EPAS1 / endothelial PAS domain protein 1 / P97481* / Q99814* / Endothelial PAS domain-containing protein 1 *  / reaction






 

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