ENSGALG00000009179


Gallus gallus

Features
Gene ID: ENSGALG00000009179
  
Biological name :TNFSF10
  
Synonyms : TNFSF10 / TNF superfamily member 10
  
Possible biological names infered from orthology : P50591 / P50592 / tumor necrosis factor (ligand) superfamily, member 10
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 19373430
Gene end: 19382089
  
Corresponding Affymetrix probe sets: Gga.8408.2.S1_s_at (Chicken Array)   Gga.8774.1.S1_s_at (Chicken Array)   Gga.8774.1.S2_at (Chicken Array)   Gga.8774.1.S2_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061754
Ensembl peptide - ENSGALP00000014937
NCBI entrez gene - 378894     See in Manteia.
RefSeq - XM_015291630
RefSeq - XM_015291627
RefSeq - XM_015291628
RefSeq - XM_015291629
RefSeq - NM_204379
RefSeq - XM_015291626
RefSeq Peptide - NP_989710
swissprot - F1NF17
swissprot - A0A1L1RSI0
Ensembl - ENSGALG00000009179
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnfsf10ENSDARG00000057241Danio rerio
 P50591ENSG00000121858Homo sapiens
 P50592ENSMUSG00000039304Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRAIL-LIKEENSGALG0000000724026
TNFSF11 / tumor necrosis factor ligand superfamily member 11 / O14788* / O35235* / TNF superfamily member 11*ENSGALG0000002616323


Protein motifs (from Interpro)
Interpro ID Name
 IPR006052  Tumour necrosis factor domain
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR017355  Tumour necrosis factor ligand 10/11
 IPR021184  Tumour necrosis factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0032813 tumor necrosis factor receptor superfamily binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation by c-FLIP
CASP8 activity is inhibited
Dimerization of procaspase-8
TRAIL signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008240 CFLAR / CASP8 and FADD-like apoptosis regulator / O15519* / O35732* / CASP8 and FADD-like apoptosis regulator CASP8 and FADD-like apoptosis regulator subunit p43 CASP8 and FADD-like apopto...  / complex / reaction
 ENSGALG00000007625 FADD / Fas associated via death domain / Q13158* / Q61160* / FAS-associated death domain protein *  / complex / reaction
 ENSGALG00000009179 TNFSF10 / TNF superfamily member 10 / P50591* / P50592* / tumor necrosis factor (ligand) superfamily, member 10*  / complex / reaction
 ENSGALG00000000452 TNFRSF10B / O14798* / Q9UBN6* / O00220* / O14763* / Q9QZM4* / TNFRSF10D* / TNFRSF10A* / TNFRSF10C* / TNF receptor superfamily member 10b* / TNF receptor superfamily member 10a* / TNF recept...  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr