ENSGALG00000010974


Gallus gallus

Features
Gene ID: ENSGALG00000010974
  
Biological name :GSC
  
Synonyms : GSC / homeobox protein goosecoid
  
Possible biological names infered from orthology : goosecoid homeobox / P56915 / Q02591
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 45795960
Gene end: 45797259
  
Corresponding Affymetrix probe sets: Gga.738.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058720
Ensembl peptide - ENSGALP00000017857
NCBI entrez gene - 396273     See in Manteia.
RefSeq - NM_205331
RefSeq Peptide - NP_990662
swissprot - F1NPM5
swissprot - A0A1L1RIZ5
Ensembl - ENSGALG00000010974
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gscENSDARG00000059073Danio rerio
 GSCENSG00000133937Homo sapiens
 GscENSMUSG00000021095Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSC2 / goosecoid homeobox 2 / O15499*ENSGALG0000004424528
PRRX1 / paired mesoderm homeobox protein 1 / P54821* / P63013* / paired related homeobox 1*ENSGALG0000000332420
PITX2 / pituitary homeobox 2 / Q99697* / P97474* / paired like homeodomain 2* / paired-like homeodomain transcription factor 2*ENSGALG0000004249220
ENSGALG0000000561319
DMBX1 / diencephalon/mesencephalon homeobox 1 / Q8NFW5* / Q91ZK4* / Diencephalon/mesencephalon homeobox protein 1 *ENSGALG0000001043619
PRRX2 / paired related homeobox 2 / Q99811*ENSGALG0000002823619
OTX1 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSGALG0000002881718
PITX1 / pituitary homeobox 1 / PITX3* / O35160* / P70314* / O75364* / P78337* / Pituitary homeobox 3 * / paired like homeodomain 1* / paired like homeodomain 3* / paired-like homeodomain t...ENSGALG0000003023717
OTX2 / orthodenticle homeobox 2 / P32243*ENSGALG0000003488917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009653 anatomical structure morphogenesis IEA
 biological_processGO:0014036 neural crest cell fate specification IEA
 biological_processGO:0021904 dorsal/ventral neural tube patterning IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0043583 ear development IEA
 biological_processGO:0048644 muscle organ morphogenesis IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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