ENSGALG00000034889


Gallus gallus

Features
Gene ID: ENSGALG00000034889
  
Biological name :OTX2
  
Synonyms : orthodenticle homeobox 2 / OTX2
  
Possible biological names infered from orthology : P32243
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 55922636
Gene end: 55929314
  
Corresponding Affymetrix probe sets: Gga.10.1.S1_at (Chicken Array)   GgaAffx.20141.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062855
Ensembl peptide - ENSGALP00000045234
NCBI entrez gene - 395191     See in Manteia.
RefSeq - XM_015287272
RefSeq - NM_204520
RefSeq Peptide - NP_989851
swissprot - Q6E236
swissprot - A0A1L1RVK3
Ensembl - ENSGALG00000034889
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otx2bENSDARG00000011235Danio rerio
 OTX2ENSG00000165588Homo sapiens
 Otx2ENSMUSG00000021848Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTX1 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSGALG0000002881771
DMBX1 / diencephalon/mesencephalon homeobox 1 / Q8NFW5* / Q91ZK4* / Diencephalon/mesencephalon homeobox protein 1 *ENSGALG0000001043628
PITX1 / pituitary homeobox 1 / PITX3* / O35160* / P70314* / O75364* / P78337* / Pituitary homeobox 3 * / paired like homeodomain 1* / paired like homeodomain 3* / paired-like homeodomain t...ENSGALG0000003023726
PITX2 / pituitary homeobox 2 / Q99697* / P97474* / paired like homeodomain 2* / paired-like homeodomain transcription factor 2*ENSGALG0000004249225
ENSGALG0000000561322
PRRX1 / paired mesoderm homeobox protein 1 / P54821* / P63013* / paired related homeobox 1*ENSGALG0000000332420
PRRX2 / paired related homeobox 2 / Q99811*ENSGALG0000002823620
GSC / homeobox protein goosecoid / P56915* / Q02591* / goosecoid homeobox*ENSGALG0000001097415
GSC2 / goosecoid homeobox 2 / O15499*ENSGALG0000004424514


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003022  Transcription factor Otx2
 IPR003025  Transcription factor Otx
 IPR009057  Homeobox-like domain superfamily
 IPR013851  Transcription factor Otx, C-terminal
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060573 cell fate specification involved in pattern specification NAS
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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