ENSGALG00000016430


Gallus gallus

Features
Gene ID: ENSGALG00000016430
  
Biological name :PDHA1
  
Synonyms : PDHA1
  
Possible biological names infered from orthology : P08559 / P29803 / P35486 / P35487 / PDHA2 / pyruvate dehydrogenase E1 alpha 1 / pyruvate dehydrogenase E1 alpha 1 subunit / pyruvate dehydrogenase E1 alpha 2 subunit / Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 120288369
Gene end: 120300358
  
Corresponding Affymetrix probe sets: Gga.18472.1.S1_at (Chicken Array)   Gga.2052.1.S1_at (Chicken Array)   Gga.2052.2.S1_at (Chicken Array)   Gga.2052.2.S1_a_at (Chicken Array)   Gga.2052.2.S1_x_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051176
Ensembl peptide - ENSGALP00000026457
NCBI entrez gene - 418610     See in Manteia.
RefSeq - XM_015302559
RefSeq - NM_001012544
RefSeq Peptide - NP_001012562
swissprot - Q5F426
swissprot - A0A1D5PEH3
Ensembl - ENSGALG00000016430
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdha1aENSDARG00000012387Danio rerio
 pdha1bENSDARG00000010555Danio rerio
 PDHA1ENSG00000131828Homo sapiens
 PDHA2ENSG00000163114Homo sapiens
 Pdha1ENSMUSG00000031299Mus musculus
 Pdha2ENSMUSG00000047674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR017597  Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
 IPR029061  Thiamin diphosphate-binding fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006086 acetyl-CoA biosynthetic process from pyruvate IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Glyoxylate metabolism and glycine degradation
Signaling by Retinoic Acid
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007904 DLAT / dihydrolipoamide S-acetyltransferase / P10515* / Q8BMF4* / Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial *  / complex
 ENSGALG00000007931 DLD / dihydrolipoamide dehydrogenase / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / complex
 ENSGALG00000016430 PDHA1 / PDHA2* / P35486* / P35487* / P08559* / P29803* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subunit* / pyruvate dehydrogenase E1 alpha 2 subunit* / Pyruv...  / complex
 ENSGALG00000029576 PDHB / pyruvate dehydrogenase E1 component subunit beta, mitochondrial / P11177* / Q9D051* / pyruvate dehydrogenase E1 beta subunit*  / complex
 ENSGALG00000009700 PDK4 / pyruvate dehydrogenase kinase 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase, isoenzyme 4*  / reaction
 ENSGALG00000016323 PDK3 / pyruvate dehydrogenase kinase 3 / Q15120* / Q922H2* / pyruvate dehydrogenase kinase, isoenzyme 3*  / reaction
 ENSGALG00000013235 PDK1 / pyruvate dehydrogenase kinase 1 / Q15118* / Q8BFP9* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *  / reaction






 

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