ENSGALG00000026853


Gallus gallus

Features
Gene ID: ENSGALG00000026853
  
Biological name :FGF3
  
Synonyms : FGF3 / Fibroblast growth factor 3 / P48801
  
Possible biological names infered from orthology : P11487
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 17620088
Gene end: 17625226
  
Corresponding Affymetrix probe sets: Gga.2701.1.S1_at (Chicken Array)   Gga.2701.1.S2_at (Chicken Array)   Gga.754.1.A1_at (Chicken Array)   Gga.754.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042296
NCBI entrez gene - 396267     See in Manteia.
RefSeq - NM_205327
RefSeq Peptide - NP_990658
swissprot - P48801
Ensembl - ENSGALG00000026853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf3ENSDARG00000101540Danio rerio
 FGF3ENSG00000186895Homo sapiens
 Fgf3ENSMUSG00000031074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780635
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487235
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366333
FGF9 / fibroblast growth factor 9 / P31371* / P54130*ENSGALG0000002574833
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSGALG0000004182231
FGF7 / fibroblast growth factor 7 / P21781* / P36363*ENSGALG0000002815830
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756229
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650827
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697127
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686625
FGF6 / fibroblast growth factor 6 / P10767* / P21658*ENSGALG0000001728725
FGF5 / fibroblast growth factor 5 / P12034* / P15656*ENSGALG0000004552124


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028232  Fibroblast growth factor 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0055026 negative regulation of cardiac muscle tissue development IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR1b ligand binding and activation
FGFR2b ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
FGFRL1 modulation of FGFR1 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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