ENSGALG00000041822


Gallus gallus

Features
Gene ID: ENSGALG00000041822
  
Biological name :FGF22
  
Synonyms : FGF22 / fibroblast growth factor 22
  
Possible biological names infered from orthology : Q9ESS2 / Q9HCT0
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2739634
Gene end: 2742740
  
Corresponding Affymetrix probe sets: GgaAffx.923.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046847
NCBI entrez gene - 100858338     See in Manteia.
RefSeq - XM_003642868
swissprot - A0A1D5P2F2
Ensembl - ENSGALG00000041822
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf22ENSDARG00000076510Danio rerio
 FGF22ENSG00000070388Homo sapiens
 Fgf22ENSMUSG00000020327Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487251
FGF7 / fibroblast growth factor 7 / P21781* / P36363*ENSGALG0000002815847
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*ENSGALG0000002685341
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366339
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780638
FGF9 / fibroblast growth factor 9 / P31371* / P54130*ENSGALG0000002574838
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756231
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697131
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650830
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686629
FGF6 / fibroblast growth factor 6 / P10767* / P21658*ENSGALG0000001728729
FGF5 / fibroblast growth factor 5 / P12034* / P15656*ENSGALG0000004552128


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028296  Fibroblast growth factor 22


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR1b ligand binding and activation
FGFR2b ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
FGFRL1 modulation of FGFR1 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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