ENSGALG00000045521


Gallus gallus

Features
Gene ID: ENSGALG00000045521
  
Biological name :FGF5
  
Synonyms : FGF5 / fibroblast growth factor 5
  
Possible biological names infered from orthology : P12034 / P15656
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 45641648
Gene end: 45643608
  
Corresponding Affymetrix probe sets: GgaAffx.6887.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058749
swissprot - A0A1L1RJ27
Ensembl - ENSGALG00000045521
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf5ENSDARG00000035377Danio rerio
 FGF5ENSG00000138675Homo sapiens
 Fgf5ENSMUSG00000029337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366333
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780632
FGF9 / fibroblast growth factor 9 / P31371* / P54130*ENSGALG0000002574832
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*ENSGALG0000002685332
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487229
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSGALG0000004182228
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650827
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756226
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686625
FGF6 / fibroblast growth factor 6 / P10767* / P21658*ENSGALG0000001728724
FGF7 / fibroblast growth factor 7 / P21781* / P36363*ENSGALG0000002815824
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697124


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028240  Fibroblast growth factor 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010001 glial cell differentiation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR3c ligand binding and activation
FGFR1c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR3
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
FGFRL1 modulation of FGFR1 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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