ENSGALG00000026971


Gallus gallus

Features
Gene ID: ENSGALG00000026971
  
Biological name :RRAGD
  
Synonyms : Ras related GTP binding D / RRAGD
  
Possible biological names infered from orthology : Q9NQL2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 75927099
Gene end: 75945917
  
Corresponding Affymetrix probe sets: GgaAffx.24771.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042542
NCBI entrez gene - 107053109     See in Manteia.
RefSeq - XM_015284701
swissprot - R4GK54
Ensembl - ENSGALG00000026971
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rragcaENSDARG00000069829Danio rerio
 RRAGDENSG00000025039Homo sapiens
 RragdENSMUSG00000028278Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRAGC / ras-related GTP-binding protein C / Q99K70* / Q9HB90* / Ras related GTP binding C*ENSGALG0000003307954


Protein motifs (from Interpro)
Interpro ID Name
 IPR006762  Gtr1/RagA G protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009267 cellular response to starvation IBA
 biological_processGO:0010506 regulation of autophagy IBA
 biological_processGO:0032008 positive regulation of TOR signaling IBA
 biological_processGO:0071230 cellular response to amino acid stimulus IBA
 biological_processGO:0071233 cellular response to leucine IEA
 biological_processGO:1904263 positive regulation of TORC1 signaling IEA
 biological_processGO:1990253 cellular response to leucine starvation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0034448 EGO complex IBA
 cellular_componentGO:1990131 Gtr1-Gtr2 GTPase complex IBA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001678 PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2 / O43741* / Q6PAM0* / protein kinase, AMP-activated, beta 2 non-catalytic subunit*  / reaction
 ENSGALG00000007373 PRKAB1 / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-activated, beta 1 non-catalytic subunit*  / reaction
 ENSGALG00000008347 ATG13 / autophagy related 13 / O75143* / Q91YI1* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / complex / reaction
 ENSGALG00000015259 RB1CC1 / RB1 inducible coiled-coil 1 / Q8TDY2* / Q9ESK9* / RB1-inducible coiled-coil protein 1 *  / complex / reaction
 ENSGALG00000014712 SLC38A9 / solute carrier family 38 member 9 / Q8BGD6* / Q8NBW4* / Sodium-coupled neutral amino acid transporter 9 *  / reaction / complex
 ENSGALG00000014832 PRKAA1 / protein kinase AMP-activated catalytic subunit alpha 1 / Q13131* / Q5EG47* / protein kinase, AMP-activated, alpha 1 catalytic subunit*  / reaction
 ENSGALG00000010826 PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2 / P54646* / Q8BRK8* / protein kinase, AMP-activated, alpha 2 catalytic subunit*  / reaction
 ENSGALG00000011360 PRKAG3 / 5-AMP-activated protein kinase subunit gamma-3 / Q9UGI9* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-activated, gamma 3 non-catat...  / reaction
 ENSGALG00000003339 MTOR / mechanistic target of rapamycin kinase / P42345* / Q9JLN9* / Serine/threonine-protein kinase mTOR *  / complex / reaction
 ENSGALG00000005878 MLST8 / MTOR associated protein, LST8 homolog / Q9BVC4* / Q9DCJ1* / Target of rapamycin complex subunit LST8 *  / complex / reaction
 ENSGALG00000036282 O54950* / P54619* / PRKAG1* / protein kinase AMP-activated non-catalytic subunit gamma 1* / protein kinase, AMP-activated, gamma 1 non-catalytic subunit*  / reaction
 ENSGALG00000004143 YWHAB / Q5ZLQ6 / 14-3-3 protein beta/alpha / Q9CQV8* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta* / tyrosine 3-monooxygenase/tryptophan 5-monoox...  / complex / reaction
 ENSGALG00000041226 RRAGB* / RRAGA* / Q7L523* / Q80X95* / Q5VZM2* / Q6NTA4* / Ras related GTP binding A* / Ras related GTP binding B* / Ras-related GTP-binding protein A * / Ras-related GTP-binding protein B *  / complex / reaction






 

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