Manteia

ENSGALG00000040880

Gallus gallus

Features

Gene ID:	ENSGALG00000040880

Biological name :	EDN3

Synonyms :	EDN3 / endothelin 3

Possible biological names infered from orthology :	P14138 / P48299

Species:	Gallus gallus

Chr. number:	20
Strand:	-1
Band:
Gene start:	11004406
Gene end:	11017978

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSGALP00000056488 NCBI entrez gene - 768509 See in Manteia. RefSeq - XM_015296553 swissprot - A0A1D5PU85 Ensembl - ENSGALG00000040880

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CR855375.3	ENSDARG00000109591	Danio rerio
edn3b	ENSDARG00000086669	Danio rerio
EDN3	ENSG00000124205	Homo sapiens
Edn3	ENSMUSG00000027524	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
EDN1 / endothelin 1 / P05305* / P22387* / Endothelin-1 Big endothelin-1*	ENSGALG00000012735	27
EDN2 / endothelin 2 / P20800* / P22389*	ENSGALG00000000667	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR001928	Endothelin-like toxin
IPR019764	Endothelin-like toxin, conserved site
IPR020475	Endothelin

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001755	neural crest cell migration	IEA
biological_process	GO:0002690	positive regulation of leukocyte chemotaxis	IEA
biological_process	GO:0003100	regulation of systemic arterial blood pressure by endothelin	IEA
biological_process	GO:0006874	cellular calcium ion homeostasis	IEA
biological_process	GO:0007166	cell surface receptor signaling pathway	IEA
biological_process	GO:0008284	positive regulation of cell proliferation	IEA
biological_process	GO:0010460	positive regulation of heart rate	IEA
biological_process	GO:0010468	regulation of gene expression	IEA
biological_process	GO:0010961	cellular magnesium ion homeostasis	IEA
biological_process	GO:0014826	vein smooth muscle contraction	IEA
biological_process	GO:0019229	regulation of vasoconstriction	IEA
biological_process	GO:0030072	peptide hormone secretion	IEA
biological_process	GO:0030182	neuron differentiation	IEA
biological_process	GO:0030318	melanocyte differentiation	IEA
biological_process	GO:0030334	regulation of cell migration	IEA
biological_process	GO:0030593	neutrophil chemotaxis	IEA
biological_process	GO:0042310	vasoconstriction	IEA
biological_process	GO:0043406	positive regulation of MAP kinase activity	IEA
biological_process	GO:0045597	positive regulation of cell differentiation	IEA
biological_process	GO:0045840	positive regulation of mitotic nuclear division	IEA
biological_process	GO:0046887	positive regulation of hormone secretion	IEA
biological_process	GO:0048016	inositol phosphate-mediated signaling	IEA
biological_process	GO:0048070	regulation of developmental pigmentation	IEA
biological_process	GO:1901381	positive regulation of potassium ion transmembrane transport	IEA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IEA
molecular_function	GO:0005179	hormone activity	IEA
molecular_function	GO:0031708	endothelin B receptor binding	IEA

Pathways (from Reactome)

Pathway description

Peptide ligand-binding receptors

G alpha (q) signalling events

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr