ENSMUSG00000000266


Mus musculus

Features
Gene ID: ENSMUSG00000000266
  
Biological name :Mid2
  
Synonyms : Mid2 / Mus musculus midline 2 (Mid2), transcript variant 2, mRNA.
  
Possible biological names infered from orthology : midline 2 / Q9UJV3
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F1
Gene start: 140664599
Gene end: 140767715
  
Corresponding Affymetrix probe sets: 10602068 (MoGene1.0st)   1422216_at (Mouse Genome 430 2.0 Array)   1450537_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108614
Ensembl peptide - ENSMUSP00000123221
Ensembl peptide - ENSMUSP00000108617
Ensembl peptide - ENSMUSP00000108612
NCBI entrez gene - 23947     See in Manteia.
MGI - MGI:1344333
RefSeq - XM_017318482
RefSeq - XM_006528522
RefSeq - XM_006528524
RefSeq - NM_001358366
RefSeq - NM_011845
RefSeq - XM_006528523
RefSeq Peptide - NP_001345295
RefSeq Peptide - NP_035975
swissprot - B1AVF6
swissprot - B1AVF4
swissprot - B1AVF5
Ensembl - ENSMUSG00000000266
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mid2ENSDARG00000034871Danio rerio
 MID2ENSGALG00000003860Gallus gallus
 MID2ENSG00000080561Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mid1 / O70583 / E3 ubiquitin-protein ligase Midline-1 / O15344* / midline 1*ENSMUSG0000003529972
Trim9 / Q8C7M3 / E3 ubiquitin-protein ligase TRIM9 / Q9C026* / tripartite motif containing 9*ENSMUSG0000002107125
Q80WG7 / Trim36 / E3 ubiquitin-protein ligase Trim36 / Q9NQ86* / tripartite motif containing 36*ENSMUSG0000003394925
Q505D9 / Trim67 / Tripartite motif-containing protein 67 / Q6ZTA4* / tripartite motif containing 67*ENSMUSG0000003691325
Q7TNM2 / Trim46 / tripartite motif-containing 46 / Q7Z4K8*ENSMUSG0000004276625
Fsd1 / Q7TPM6 / Fibronectin type III and SPRY domain-containing protein 1 / Q9BTV5* / fibronectin type III and SPRY domain containing 1*ENSMUSG0000001158919
Fsd1l / Q8BYN5 / Mus musculus fibronectin type III and SPRY domain containing 1-like (Fsd1l), transcript variant 3, mRNA. / Q9BXM9* / fibronectin type III and SPRY domain containing 1 like*ENSMUSG0000005475218
Trim55 / tripartite motif-containing 55 / Q9BYV6*ENSMUSG0000006091317
Trim63 / tripartite motif-containing 63 / Q969Q1*ENSMUSG0000002883415
Q9ERP3 / Trim54 / Tripartite motif-containing protein 54 / Q9BYV2* / tripartite motif containing 54*ENSMUSG0000006207714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003649  B-box, C-terminal
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR003961  Fibronectin type III
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR017903  COS domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR033491  Probable E3 ubiquitin-protein ligase MID2
 IPR035752  TRIM1, PRY/SPRY domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010508 positive regulation of autophagy IEA
 biological_processGO:0032897 negative regulation of viral transcription IEA
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:1902187 negative regulation of viral release from host cell IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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