ENSMUSG00000000318


Mus musculus

Features
Gene ID: ENSMUSG00000000318
  
Biological name :Clec10a
  
Synonyms : Clec10a / C-type lectin domain family 10 member A / P49300
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 70156197
Gene end: 70170834
  
Corresponding Affymetrix probe sets: 10377782 (MoGene1.0st)   1419605_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115739
Ensembl peptide - ENSMUSP00000137447
Ensembl peptide - ENSMUSP00000136500
Ensembl peptide - ENSMUSP00000136322
Ensembl peptide - ENSMUSP00000117772
Ensembl peptide - ENSMUSP00000000327
Ensembl peptide - ENSMUSP00000099631
NCBI entrez gene - 17312     See in Manteia.
MGI - MGI:96975
RefSeq - NM_001204252
RefSeq - NM_010796
RefSeq Peptide - NP_001191181
RefSeq Peptide - NP_034926
swissprot - J3QPR7
swissprot - B1AU03
swissprot - P49300
swissprot - B1AU01
swissprot - A2CF65
swissprot - A2CF63
swissprot - F8WHB7
Ensembl - ENSMUSG00000000318
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-283g2.2ENSDARG00000108953Danio rerio
 si:ch211-283g2.3ENSDARG00000046092Danio rerio
 si:ch73-361h17.1ENSDARG00000095963Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mgl2ENSMUSG0000004095089
Asgr1 / P34927 / Asialoglycoprotein receptor 1 / P07306*ENSMUSG0000002088448
Asgr2 / P24721 / Asialoglycoprotein receptor 2 / P07307*ENSMUSG0000004096340
Clec4f / Q8N1N0* / C-type lectin domain family 4 member F*ENSMUSG0000001454226
P20693 / Fcer2a / Low affinity immunoglobulin epsilon Fc receptor / FCER2* / P06734* / Fc fragment of IgE receptor II*ENSMUSG0000000554022
Q91ZX1 / Cd209a / CD209 antigen-like protein A / CD209* / Q9NNX6* / CLEC4M* / Q9H2X3* / CD209 molecule* / C-type lectin domain family 4 member M*ENSMUSG0000003149422
Q91ZW7 / Cd209e / CD209 antigen-like protein E / CD209* / Q9NNX6* / CLEC4M* / Q9H2X3* / CD209 molecule* / C-type lectin domain family 4 member M*ENSMUSG0000004019721
Cd209f / CD209f antigenENSMUSG0000005190621
Clec4g / Q8BNX1 / C-type lectin domain family 4 member G / Q6UXB4*ENSMUSG0000007449121
Clec4e / Q9R0Q8 / C-type lectin domain family 4 member E / Q9ULY5*ENSMUSG0000003014220
Cd207 / Q8VBX4 / C-type lectin domain family 4 member K / Q9UJ71* / CD207 molecule*ENSMUSG0000003478320
Q91ZW8 / Cd209d / CD209 antigen-like protein D / CD209* / Q9NNX6* / CLEC4M* / Q9H2X3* / CD209 molecule* / C-type lectin domain family 4 member M*ENSMUSG0000003149519
Q8CJ91 / Cd209b / CD209 antigen-like protein B / CD209* / Q9NNX6* / CLEC4M* / Q9H2X3* / CD209 molecule* / C-type lectin domain family 4 member M*ENSMUSG0000006598719
Cd209g / CD209g antigenENSMUSG0000007916818
Q91ZW9 / Cd209c / CD209 antigen-like protein C / CD209* / Q9NNX6* / CLEC4M* / Q9H2X3* / CD209 molecule* / C-type lectin domain family 4 member M*ENSMUSG0000004016517


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002248 connective tissue replacement involved in inflammatory response wound healing IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003131 increased erythrocyte count "greater number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Efnb1tm4.2Sor/Efnb1+
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Clec10atm1Hed/Clec10a+,St3gal1tm1Jxm/St3gal1tm1Jxm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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