ENSMUSG00000016018


Mus musculus

Features
Gene ID: ENSMUSG00000016018
  
Biological name :Skiv2l2
  
Synonyms : Q9CZU3 / Skiv2l2 / Superkiller viralicidic activity 2-like 2
  
Possible biological names infered from orthology : Mtr4 exosome RNA helicase / MTREX / P42285
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D2.2
Gene start: 112867418
Gene end: 112927398
  
Corresponding Affymetrix probe sets: 10412177 (MoGene1.0st)   1426718_at (Mouse Genome 430 2.0 Array)   1437971_at (Mouse Genome 430 2.0 Array)   1447517_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022281
NCBI entrez gene - 72198     See in Manteia.
MGI - MGI:1919448
RefSeq - NM_028151
RefSeq Peptide - NP_082427
swissprot - Q9CZU3
Ensembl - ENSMUSG00000016018
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtrexENSDARG00000013457Danio rerio
 SKIV2L2ENSGALG00000014709Gallus gallus
 MTREXENSG00000039123Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Skiv2l / superkiller viralicidic activity 2-like (S. cerevisiae) / Q15477* / Ski2 like RNA helicase*ENSMUSG0000004035636
Ddx60 / DExD/H-box helicase 60 / Q8IY21*ENSMUSG0000003792119


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR012961  ATP-dependent RNA helicase Ski2, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016438  ATP-dependent RNA helicase Ski2-like
 IPR025696  rRNA-processing arch domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000460 maturation of 5.8S rRNA IEA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006401 RNA catabolic process IBA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003724 RNA helicase activity IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000581 C1d / O35473 / Mus musculus C1D nuclear receptor co-repressor (C1d), transcript variant 2, mRNA. / Q13901* / C1D nuclear receptor corepressor*  / complex
 ENSMUSG00000017264 P56960 / Exosc10 / Mus musculus exosome component 10 (Exosc10), transcript variant 5, mRNA. / Q01780* / exosome component 10*  / complex
 ENSMUSG00000031843 Q9D1Q1 / Mphosph6 / Mus musculus M phase phosphoprotein 6 (Mphosph6), transcript variant 3, mRNA. / Q99547* / M-phase phosphoprotein 6*  / complex






 

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