ENSMUSG00000022066


Mus musculus
membraneEntpd4bactivitygolgiintegralcomponentautophagosomenucleosidephosphatasegdacdapparatuscytoplasmicvesiclehydrolasenucleoside-diphosphatasenucleoside-triphosphataseuridine-diphosphatasephosphatebondhydrolysisntpdaseproteins

Features
Gene ID: ENSMUSG00000022066
  
Biological name :Entpd4b
  
Synonyms : Ectonucleoside triphosphate diphosphohydrolase 4 / Entpd4b / Q9DBT4
  
Possible biological names infered from orthology : ENTPD4 / Q9Y227
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D2
Gene start: 69555424
Gene end: 69585520
  
Corresponding Affymetrix probe sets: 10416199 (MoGene1.0st)   1438177_x_at (Mouse Genome 430 2.0 Array)   1449190_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000063726
Ensembl peptide - ENSMUSP00000139202
NCBI entrez gene - 100862375     See in Manteia.
MGI - MGI:5435040
RefSeq - XM_003688929
RefSeq - XM_003688928
RefSeq Peptide - NP_001346088
swissprot - Q9DBT4
swissprot - Q80WR8
Ensembl - ENSMUSG00000022066
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd4ENSDARG00000038422Danio rerio
 ENTPD4ENSGALG00000000390Gallus gallus
 ENTPD4ENSG00000197217Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Entpd4 / Q9DBT4 / Ectonucleoside triphosphate diphosphohydrolase 4 / Q9Y227*ENSMUSG00000095463100
Entpd7 / Q3TCT4 / Ectonucleoside triphosphate diphosphohydrolase 7 / Q9NQZ7*ENSMUSG0000002519261
Entpd2 / O55026 / Ectonucleoside triphosphate diphosphohydrolase 2 / Q9Y5L3*ENSMUSG0000001508521
Entpd8 / Q8K0L2 / Ectonucleoside triphosphate diphosphohydrolase 8 / Q5MY95*ENSMUSG0000003681321
Entpd1 / P55772 / Ectonucleoside triphosphate diphosphohydrolase 1 / P49961* / AL365273.2*ENSMUSG0000004812021
Entpd3 / ectonucleoside triphosphate diphosphohydrolase 3 / O75355*ENSMUSG0000004160820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
hydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activity
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0097637 integral component of autophagosome membrane ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity ISO
 molecular_functionGO:0017111 nucleoside-triphosphatase activity ISO
 molecular_functionGO:0045134 uridine-diphosphatase activity ISO


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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