ENSMUSG00000036813


Mus musculus

Features
Gene ID: ENSMUSG00000036813
  
Biological name :Entpd8
  
Synonyms : Ectonucleoside triphosphate diphosphohydrolase 8 / Entpd8 / Q8K0L2
  
Possible biological names infered from orthology : Q5MY95
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 25080304
Gene end: 25085716
  
Corresponding Affymetrix probe sets: 10469923 (MoGene1.0st)   1429550_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040628
Ensembl peptide - ENSMUSP00000110017
Ensembl peptide - ENSMUSP00000110022
Ensembl peptide - ENSMUSP00000142316
NCBI entrez gene - 72090     See in Manteia.
MGI - MGI:1919340
RefSeq - XM_011239193
RefSeq - NM_028093
RefSeq - XM_006498362
RefSeq - XM_011239191
RefSeq - XM_011239192
RefSeq Peptide - NP_082369
swissprot - Q8K0L2
swissprot - A0A0A6YY80
Ensembl - ENSMUSG00000036813
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 entpd8ENSDARG00000005565Danio rerio
 ENSGALG00000008936Gallus gallus
 ENTPD8ENSGALG00000008932Gallus gallus
 ENTPD8ENSG00000188833Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Entpd2 / O55026 / Ectonucleoside triphosphate diphosphohydrolase 2 / Q9Y5L3*ENSMUSG0000001508544
Entpd1 / P55772 / Ectonucleoside triphosphate diphosphohydrolase 1 / P49961* / AL365273.2*ENSMUSG0000004812042
Entpd3 / ectonucleoside triphosphate diphosphohydrolase 3 / O75355*ENSMUSG0000004160839
Entpd7 / Q3TCT4 / Ectonucleoside triphosphate diphosphohydrolase 7 / Q9NQZ7*ENSMUSG0000002519226
Q9DBT4 / Entpd4b / Ectonucleoside triphosphate diphosphohydrolase 4 / ENTPD4* / Q9Y227*ENSMUSG0000002206625
Entpd4 / Q9DBT4 / Ectonucleoside triphosphate diphosphohydrolase 4 / Q9Y227*ENSMUSG0000009546325


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009124 nucleoside monophosphate biosynthetic process IDA
 biological_processGO:0009133 nucleoside diphosphate biosynthetic process IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity ISO
 molecular_functionGO:0017111 nucleoside-triphosphatase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0102485 dATP phosphohydrolase activity IEA
 molecular_functionGO:0102486 dCTP phosphohydrolase activity IEA
 molecular_functionGO:0102487 dUTP phosphohydrolase activity IEA
 molecular_functionGO:0102488 dTTP phosphohydrolase activity IEA
 molecular_functionGO:0102489 GTP phosphohydrolase activity IEA
 molecular_functionGO:0102490 8-oxo-dGTP phosphohydrolase activity IEA
 molecular_functionGO:0102491 dGTP phosphohydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Egr1tm1b(NCOM)Mfgc/Egr1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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