ENSMUSG00000025192


Mus musculus

Features
Gene ID: ENSMUSG00000025192
  
Biological name :Entpd7
  
Synonyms : Ectonucleoside triphosphate diphosphohydrolase 7 / Entpd7 / Q3TCT4
  
Possible biological names infered from orthology : Q9NQZ7
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 43689672
Gene end: 43733697
  
Corresponding Affymetrix probe sets: 10463282 (MoGene1.0st)   1431179_at (Mouse Genome 430 2.0 Array)   1432068_a_at (Mouse Genome 430 2.0 Array)   1435625_at (Mouse Genome 430 2.0 Array)   1436623_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079864
NCBI entrez gene - 93685     See in Manteia.
MGI - MGI:2135885
RefSeq - NM_053103
RefSeq Peptide - NP_444333
swissprot - Q3TCT4
Ensembl - ENSMUSG00000025192
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENTPD7ENSGALG00000023691Gallus gallus
 ENTPD7ENSG00000198018Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9DBT4 / Entpd4b / Ectonucleoside triphosphate diphosphohydrolase 4 / ENTPD4* / Q9Y227*ENSMUSG0000002206662
Entpd4 / Q9DBT4 / Ectonucleoside triphosphate diphosphohydrolase 4 / Q9Y227*ENSMUSG0000009546362
Entpd2 / O55026 / Ectonucleoside triphosphate diphosphohydrolase 2 / Q9Y5L3*ENSMUSG0000001508522
Entpd8 / Q8K0L2 / Ectonucleoside triphosphate diphosphohydrolase 8 / Q5MY95*ENSMUSG0000003681321
Entpd3 / ectonucleoside triphosphate diphosphohydrolase 3 / O75355*ENSMUSG0000004160821
Entpd1 / P55772 / Ectonucleoside triphosphate diphosphohydrolase 1 / P49961* / AL365273.2*ENSMUSG0000004812020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000407  Nucleoside phosphatase GDA1/CD39


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009191 ribonucleoside diphosphate catabolic process ISO
 biological_processGO:0009203 ribonucleoside triphosphate catabolic process ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity ISO
 molecular_functionGO:0017111 nucleoside-triphosphatase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NTPDase proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6

 MP:0004799 increased susceptibility to experimental autoimmune encephalomyelitis "greater likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6

 MP:0008073 abnormal CD4-positive T cell number "anomaly in the number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6

 MP:0010155 abnormal intestine physiology "any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6

 MP:0010219 increased T-helper 17 cell number "increased number of CD4-positive, alpha-beta T cells with the phenotype RORgamma-t-positive that produces IL-17" [CL:0000899]
Show

Allelic Composition: Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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