ENSMUSG00000025091


Mus musculus

Features
Gene ID: ENSMUSG00000025091
  
Biological name :Pnliprp2
  
Synonyms : P17892 / pancreatic lipase-related protein 2 / Pnliprp2
  
Possible biological names infered from orthology : pancreatic lipase related protein 2 (gene/pseudogene)
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D2
Gene start: 58759723
Gene end: 58777533
  
Corresponding Affymetrix probe sets: 10464328 (MoGene1.0st)   1437438_x_at (Mouse Genome 430 2.0 Array)   1448186_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026081
NCBI entrez gene - 18947     See in Manteia.
MGI - MGI:1336202
RefSeq - NM_011128
RefSeq Peptide - NP_035258
swissprot - P17892
Ensembl - ENSMUSG00000025091
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PNLIPENSGALG00000009231Gallus gallus
 PNLIPRP2ENSG00000266200Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pnlip / Q6P8U6 / pancreatic lipase / P16233*ENSMUSG0000004600866
Q5BKQ4 / Pnliprp1 / pancreatic lipase related protein 1 / P54315*ENSMUSG0000004217961
Liph / Q8CIV3 / Lipase member H / Q8WWY8* / lipase H*ENSMUSG0000004462627
Pla1a / Q8VI78 / Phospholipase A1 member A / Q53H76*ENSMUSG0000000284726
Lipc / P27656 / Hepatic triacylglycerol lipase / P11150* / lipase C, hepatic type*ENSMUSG0000003220726
Lipg / Q9WVG5 / Endothelial lipase / Q9Y5X9* / lipase G, endothelial type*ENSMUSG0000005384626
Lpl / P11152 / lipoprotein lipase / P06858*ENSMUSG0000001556825
Lipi / lipase I / Q6XZB0*ENSMUSG0000003294825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR001024  PLAT/LH2 domain
 IPR002331  Pancreatic lipase
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal
 IPR036392  PLAT/LH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006968 cellular defense response IMP
 biological_processGO:0007586 digestion IMP
 biological_processGO:0009395 phospholipid catabolic process ISS
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019376 galactolipid catabolic process ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISS
 molecular_functionGO:0004620 phospholipase activity ISS
 molecular_functionGO:0004806 triglyceride lipase activity IDA
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047372 acylglycerol lipase activity ISS
 molecular_functionGO:0047714 galactolipase activity ISO
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA
 molecular_functionGO:0102549 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dnase2atm1Aea/Dnase2atm1Aea
Genetic Background: involves: 129 * C57BL/6

 MP:0005079 defective cytotoxic T cell cytolysis "impaired ability of these cells to destroy or dissolve targeted cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:6692]
Show

Allelic Composition: Dnase2atm1Aea/Dnase2atm1Aea
Genetic Background: involves: 129 * C57BL/6

 MP:0005342 abnormal lipid absorption "anomalous ability of the body to take in fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Dnase2atm1Aea/Dnase2atm1Aea
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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