ENSMUSG00000044626


Mus musculus

Features
Gene ID: ENSMUSG00000044626
  
Biological name :Liph
  
Synonyms : Lipase member H / Liph / Q8CIV3
  
Possible biological names infered from orthology : lipase H / Q8WWY8
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B1
Gene start: 21953826
Gene end: 21995542
  
Corresponding Affymetrix probe sets: 10438592 (MoGene1.0st)   1456619_at (Mouse Genome 430 2.0 Array)   1457026_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073853
Ensembl peptide - ENSMUSP00000062310
NCBI entrez gene - 239759     See in Manteia.
MGI - MGI:2388029
RefSeq - NM_153404
RefSeq - XM_017316982
RefSeq - NM_001083894
RefSeq - NM_001289581
RefSeq - NM_001289582
RefSeq Peptide - NP_001276510
RefSeq Peptide - NP_001276511
RefSeq Peptide - NP_700453
RefSeq Peptide - NP_001077363
swissprot - Q8CIV3
Ensembl - ENSMUSG00000044626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lipiaENSDARG00000007108Danio rerio
 lipibENSDARG00000005332Danio rerio
 LIPHENSGALG00000038601Gallus gallus
 LIPHENSG00000163898Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lipi / lipase I / Q6XZB0*ENSMUSG0000003294841
Pla1a / Q8VI78 / Phospholipase A1 member A / Q53H76*ENSMUSG0000000284731
Q5BKQ4 / Pnliprp1 / pancreatic lipase related protein 1 / P54315*ENSMUSG0000004217930
P17892 / Pnliprp2 / pancreatic lipase-related protein 2 / pancreatic lipase related protein 2 (gene/pseudogene)*ENSMUSG0000002509129
Lipg / Q9WVG5 / Endothelial lipase / Q9Y5X9* / lipase G, endothelial type*ENSMUSG0000005384628
Lipc / P27656 / Hepatic triacylglycerol lipase / P11150* / lipase C, hepatic type*ENSMUSG0000003220727
Pnlip / Q6P8U6 / pancreatic lipase / P16233*ENSMUSG0000004600827
Lpl / P11152 / lipoprotein lipase / P06858*ENSMUSG0000001556826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0000410 waved hair "hair or fur having undulations or a sinusoidal shape" [J:47620]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0001279 wavy vibrissae "whiskers having undulations or a sinusoidal shape" [J:65044]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0003810 abnormal hair cuticle "anomalies in the thin, smooth and glossy outer protective cell layer of hair shaft" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0003812 abnormal hair medulla "anomalies of hair medullary cell formation and arrangement of the innermost core of the hair shaft " [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0003846 matted coat "coat hairs sticks together to form clumps and does not lie flat" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0008731 abnormal hair shaft melanin granules "any amount or distribution anomaly of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0010685 abnormal hair follicle inner root sheath morphology "any structural anomaly of the multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle s layer, Huxley s layer and the inner root sheath cuticle" [PMID:19211055]
Show

Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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