ENSMUSG00000032948


Mus musculus

Features
Gene ID: ENSMUSG00000032948
  
Biological name :Lipi
  
Synonyms : lipase I / Lipi
  
Possible biological names infered from orthology : Q6XZB0
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C3.1
Gene start: 75540514
Gene end: 75586061
  
Corresponding Affymetrix probe sets: 10440376 (MoGene1.0st)   1444427_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053447
NCBI entrez gene - 320355     See in Manteia.
MGI - MGI:2443868
RefSeq - XM_011246135
RefSeq - NM_001252513
RefSeq - XM_011246133
RefSeq - XM_011246134
RefSeq Peptide - NP_001239442
swissprot - F6YQT7
Ensembl - ENSMUSG00000032948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lipiaENSDARG00000007108Danio rerio
 lipibENSDARG00000005332Danio rerio
 LIPIENSGALG00000015662Gallus gallus
 LIPIENSG00000188992Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Liph / Q8CIV3 / Lipase member H / Q8WWY8* / lipase H*ENSMUSG0000004462639
Pla1a / Q8VI78 / Phospholipase A1 member A / Q53H76*ENSMUSG0000000284729
Q5BKQ4 / Pnliprp1 / pancreatic lipase related protein 1 / P54315*ENSMUSG0000004217926
Pnlip / Q6P8U6 / pancreatic lipase / P16233*ENSMUSG0000004600826
Lipg / Q9WVG5 / Endothelial lipase / Q9Y5X9* / lipase G, endothelial type*ENSMUSG0000005384626
P17892 / Pnliprp2 / pancreatic lipase-related protein 2 / pancreatic lipase related protein 2 (gene/pseudogene)*ENSMUSG0000002509125
Lipc / P27656 / Hepatic triacylglycerol lipase / P11150* / lipase C, hepatic type*ENSMUSG0000003220725
Lpl / P11152 / lipoprotein lipase / P06858*ENSMUSG0000001556824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000734  Triacylglycerol lipase family
 IPR013818  Lipase/vitellogenin
 IPR016272  Lipase, LIPH-type
 IPR029058  Alpha/Beta hydrolase fold
 IPR033906  Lipase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000424 retarded hair growth "slow growth of the hair, appears at normal time" [J:5476]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pax6tm2Pgr/Pax6tm2Pgr,Tg(Pdx1-cre)6Cvw/0
Genetic Background: involves: FVB * NMRI

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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