ENSMUSG00000031143


Mus musculus

Features
Gene ID: ENSMUSG00000031143
  
Biological name :Ccdc22
  
Synonyms : Ccdc22 / Coiled-coil domain-containing protein 22 / Q9JIG7
  
Possible biological names infered from orthology : coiled-coil domain containing 22 / O60826
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.1
Gene start: 7593809
Gene end: 7605517
  
Corresponding Affymetrix probe sets: 10603328 (MoGene1.0st)   1418347_at (Mouse Genome 430 2.0 Array)   1447759_x_at (Mouse Genome 430 2.0 Array)   1455805_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033483
NCBI entrez gene - 54638     See in Manteia.
MGI - MGI:1859608
RefSeq - NM_138603
RefSeq Peptide - NP_613069
swissprot - Q9JIG7
Ensembl - ENSMUSG00000031143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccdc22ENSDARG00000052379Danio rerio
 CCDC22ENSG00000101997Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008530  Coiled-coil domain-containing protein 22


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006878 cellular copper ion homeostasis IEA
 biological_processGO:0006893 Golgi to plasma membrane transport IEA
 biological_processGO:0007253 cytoplasmic sequestering of NF-kappaB IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042632 cholesterol homeostasis ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0097006 regulation of plasma lipoprotein particle levels ISO
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005768 endosome IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0097602 cullin family protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005575 Ube2m / P61082 / ubiquitin-conjugating enzyme E2M / P61081*  / complex
 ENSMUSG00000010376 Nedd8 / P29595 / Q15843* / neural precursor cell expressed, developmentally down-regulated 8*  / complex
 ENSMUSG00000020114 Cand1 / Q6ZQ38 / Cullin-associated NEDD8-dissociated protein 1 / Q86VP6* / cullin associated and neddylation dissociated 1*  / reaction
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / reaction / complex
 ENSMUSG00000025917 Cops5 / O35864 / COP9 signalosome complex subunit 5 / Q92905* / COP9 signalosome subunit 5*  / reaction
 ENSMUSG00000031446 Cul4a / Q3TCH7 / Cullin-4A / Q13619*  / complex / reaction
 ENSMUSG00000031095 Cul4b / A2A432 / Cullin-4B / Q13620*  / complex / reaction
 ENSMUSG00000024740 Ddb1 / Q3U1J4 / DNA damage-binding protein 1 / Q16531* / damage specific DNA binding protein 1*  / complex / reaction
 ENSMUSG00000029686 Cul1 / Q9WTX6 / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA. / Q13616* / cullin 1*  / complex / reaction
 ENSMUSG00000036309 Skp1a / Q9WTX5 / S-phase kinase-associated protein 1A / SKP1* / P63208* / AC104109.3* / S-phase kinase associated protein 1*  / complex / reaction
 ENSMUSG00000051355 Commd1 / Q8K4M5 / COMM domain-containing protein 1 / Q8N668* / copper metabolism domain containing 1*  / complex
 ENSMUSG00000048787 Q8K0V2 / Dcun1d3 / DCN1-like protein 3 / Q8IWE4* / defective in cullin neddylation 1 domain containing 3*  / complex / reaction
 ENSMUSG00000004364 Cul3 / Q9JLV5 / Cullin-3 / Q13618*  / complex / reaction
 ENSMUSG00000034343 Ube2f / Q9CY34 / ubiquitin-conjugating enzyme E2F (putative) / Q969M7*  / complex






 

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