ENSMUSG00000032047


Mus musculus

Features
Gene ID: ENSMUSG00000032047
  
Biological name :Acat1
  
Synonyms : Acat1 / Acetyl-CoA acetyltransferase, mitochondrial / Q8QZT1
  
Possible biological names infered from orthology : acetyl-CoA acetyltransferase 1 / P24752
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.3
Gene start: 53580522
Gene end: 53610382
  
Corresponding Affymetrix probe sets: 10593591 (MoGene1.0st)   1424182_at (Mouse Genome 430 2.0 Array)   1424183_at (Mouse Genome 430 2.0 Array)   1451271_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034547
NCBI entrez gene - 110446     See in Manteia.
MGI - MGI:87870
RefSeq - NM_144784
RefSeq Peptide - NP_659033
swissprot - Q8QZT1
Ensembl - ENSMUSG00000032047
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acat1ENSDARG00000045888Danio rerio
 ACAT1ENSGALG00000017163Gallus gallus
 ACAT1ENSG00000075239Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acat2 / Q8CAY6 / acetyl-Coenzyme A acetyltransferase 2 / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000002383240
Acat3 / acetyl-Coenzyme A acetyltransferase 3 / ACAT2* / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000006248040
Acaa2 / Q8BWT1 / 3-ketoacyl-CoA thiolase, mitochondrial / P42765* / acetyl-CoA acyltransferase 2*ENSMUSG0000003688036


Protein motifs (from Interpro)
Interpro ID Name
 IPR002155  Thiolase
 IPR016039  Thiolase-like
 IPR020610  Thiolase, active site
 IPR020613  Thiolase, conserved site
 IPR020615  Thiolase, acyl-enzyme intermediate active site
 IPR020616  Thiolase, N-terminal
 IPR020617  Thiolase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006085 acetyl-CoA biosynthetic process IEA
 biological_processGO:0006550 isoleucine catabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IBA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0015936 coenzyme A metabolic process IEA
 biological_processGO:0015937 coenzyme A biosynthetic process IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0046356 acetyl-CoA catabolic process IEA
 biological_processGO:0046952 ketone body catabolic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0072229 metanephric proximal convoluted tubule development IEA
 biological_processGO:1902860 propionyl-CoA biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003985 acetyl-CoA C-acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA
 molecular_functionGO:0016830 carbon-carbon lyase activity IEA
 molecular_functionGO:0016885 ligase activity, forming carbon-carbon bonds IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050662 coenzyme binding IEA


Pathways (from Reactome)
Pathway description
Branched-chain amino acid catabolism
Utilization of Ketone Bodies
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032047 Acat1 / Q8QZT1 / Acetyl-CoA acetyltransferase, mitochondrial / P24752* / acetyl-CoA acetyltransferase 1*  / complex






 

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