ENSMUSG00000036880


Mus musculus

Features
Gene ID: ENSMUSG00000036880
  
Biological name :Acaa2
  
Synonyms : 3-ketoacyl-CoA thiolase, mitochondrial / Acaa2 / Q8BWT1
  
Possible biological names infered from orthology : acetyl-CoA acyltransferase 2 / P42765
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E2
Gene start: 74779197
Gene end: 74806207
  
Corresponding Affymetrix probe sets: 10456699 (MoGene1.0st)   1428145_at (Mouse Genome 430 2.0 Array)   1428146_s_at (Mouse Genome 430 2.0 Array)   1455061_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037348
NCBI entrez gene - 52538     See in Manteia.
MGI - MGI:1098623
RefSeq - NM_177470
RefSeq Peptide - NP_803421
swissprot - Q8BWT1
Ensembl - ENSMUSG00000036880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acaa2ENSDARG00000038881Danio rerio
 ACAA2ENSGALG00000031142Gallus gallus
 ACAA2ENSG00000167315Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acat2 / Q8CAY6 / acetyl-Coenzyme A acetyltransferase 2 / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000002383240
Acat3 / acetyl-Coenzyme A acetyltransferase 3 / ACAT2* / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000006248039
Acat1 / Q8QZT1 / Acetyl-CoA acetyltransferase, mitochondrial / P24752* / acetyl-CoA acetyltransferase 1*ENSMUSG0000003204738


Protein motifs (from Interpro)
Interpro ID Name
 IPR002155  Thiolase
 IPR016039  Thiolase-like
 IPR020610  Thiolase, active site
 IPR020613  Thiolase, conserved site
 IPR020615  Thiolase, acyl-enzyme intermediate active site
 IPR020616  Thiolase, N-terminal
 IPR020617  Thiolase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IEA
 biological_processGO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003988 acetyl-CoA C-acyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036880 Acaa2 / Q8BWT1 / 3-ketoacyl-CoA thiolase, mitochondrial / P42765* / acetyl-CoA acyltransferase 2*  / complex






 

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