ENSMUSG00000062480


Mus musculus

Features
Gene ID: ENSMUSG00000062480
  
Biological name :Acat3
  
Synonyms : Acat3 / acetyl-Coenzyme A acetyltransferase 3
  
Possible biological names infered from orthology : ACAT2 / acetyl-CoA acetyltransferase 2 / Q9BWD1
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A1
Gene start: 12923833
Gene end: 12940402
  
Corresponding Affymetrix probe sets: 10447885 (MoGene1.0st)   1425195_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045912
Ensembl peptide - ENSMUSP00000125454
NCBI entrez gene - 224530     See in Manteia.
MGI - MGI:109182
RefSeq - NM_153151
RefSeq Peptide - NP_694791
swissprot - F2Z459
swissprot - Q80X81
Ensembl - ENSMUSG00000062480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acat2ENSDARG00000007127Danio rerio
 ACAT2ENSGALG00000011659Gallus gallus
 ACAT2ENSG00000120437Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acat2 / Q8CAY6 / acetyl-Coenzyme A acetyltransferase 2 / Q9BWD1* / acetyl-CoA acetyltransferase 2*ENSMUSG0000002383298
Acat1 / Q8QZT1 / Acetyl-CoA acetyltransferase, mitochondrial / P24752* / acetyl-CoA acetyltransferase 1*ENSMUSG0000003204742
Acaa2 / Q8BWT1 / 3-ketoacyl-CoA thiolase, mitochondrial / P42765* / acetyl-CoA acyltransferase 2*ENSMUSG0000003688039


Protein motifs (from Interpro)
Interpro ID Name
 IPR002155  Thiolase
 IPR016039  Thiolase-like
 IPR020610  Thiolase, active site
 IPR020613  Thiolase, conserved site
 IPR020616  Thiolase, N-terminal
 IPR020617  Thiolase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006635 fatty acid beta-oxidation IBA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003985 acetyl-CoA C-acetyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups IEA


Pathways (from Reactome)
Pathway description
Cholesterol biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023832 Acat2 / Q8CAY6 / acetyl-Coenzyme A acetyltransferase 2 / Q9BWD1* / acetyl-CoA acetyltransferase 2*  / complex
 ENSMUSG00000062480 Acat3 / acetyl-Coenzyme A acetyltransferase 3 / ACAT2* / Q9BWD1* / acetyl-CoA acetyltransferase 2*  / complex






 

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