MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002675 | asthenozoospermia | "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004542 | impaired acrosome reaction | "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004543 | abnormal sperm physiology | "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009237 | kinked sperm flagellum | "a sharp bend or zigzag in the sperm tail" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009242 | thin sperm flagellum | "reduced thickness of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009243 | hairpin sperm flagellum | "a structural alteration where the sperm flagellum becomes bent back (folded) on itself to form a hairpin (loop) structure; a sharp hairpin-like bend formation can disrupt the axial structures and cause the sperm tail to become kinked" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009831 | abnormal sperm midpiece morphology | "any structural abnormality of the highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece" [PMID:14581499] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009832 | abnormal sperm mitochondrial sheath morphology | "any structural anomaly or impairment of the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum" [PMID:14581499] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009834 | abnormal sperm annulus morphology | "any structural anomaly of the ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity" [PMID:14581499] |
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Allelic Composition: Hace1tm1Pngr/Hace1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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