ENSMUSG00000042268


Mus musculus

Features
Gene ID: ENSMUSG00000042268
  
Biological name :Slc26a9
  
Synonyms : Slc26a9 / solute carrier family 26 member 9
  
Possible biological names infered from orthology : Q7LBE3
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 131744022
Gene end: 131771504
  
Corresponding Affymetrix probe sets: 10349671 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000036916
Ensembl peptide - ENSMUSP00000141171
Ensembl peptide - ENSMUSP00000122075
NCBI entrez gene - 320718     See in Manteia.
MGI - MGI:2444594
RefSeq - XM_006529701
RefSeq - NM_177243
RefSeq - XM_006529700
RefSeq Peptide - NP_796217
swissprot - D3Z1A3
swissprot - A0A087WSS7
swissprot - A0A0R4J0F7
Ensembl - ENSMUSG00000042268
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC26A9ENSGALG00000000745Gallus gallus
 Q7LBE3ENSG00000174502Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9WVC8 / Slc26a3 / Chloride anion exchanger / P40879* / solute carrier family 26 member 3*ENSMUSG0000000122533
Q9R155 / Slc26a4 / Pendrin / O43511* / solute carrier family 26 member 4*ENSMUSG0000002065132
Q99NH7 / Slc26a5 / Prestin / P58743* / solute carrier family 26 member 5*ENSMUSG0000002901532
Slc26a6 / solute carrier family 26, member 6 / Q9BXS9*ENSMUSG0000002325931
Q62273 / Slc26a2 / Sulfate transporter / P50443* / solute carrier family 26 member 2*ENSMUSG0000003432027
Q8R0C3 / Slc26a8 / Testis anion transporter 1 / Q96RN1* / solute carrier family 26 member 8*ENSMUSG0000003619625
Slc26a10 / solute carrier family 26 member 10 / Q8NG04*ENSMUSG0000004044124
P58735 / Slc26a1 / solute carrier family 26 (sulfate transporter), member 1 / Q9H2B4* / solute carrier family 26 member 1*ENSMUSG0000004695924
Q8R2Z3 / Slc26a7 / Anion exchange transporter / Q8TE54* / solute carrier family 26 member 7*ENSMUSG0000004056923


Protein motifs (from Interpro)
Interpro ID Name
 IPR001902  SLC26A/SulP transporter
 IPR002645  STAS domain
 IPR011547  SLC26A/SulP transporter domain
 IPR030306  Solute carrier family 26 member 9
 IPR036513  STAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0008272 sulfate transport IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:1902358 sulfate transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0008271 secondary active sulfate transmembrane transporter activity IEA
 molecular_functionGO:0015116 sulfate transmembrane transporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IEA
 molecular_functionGO:0051117 ATPase binding IEA


Pathways (from Reactome)
Pathway description
Multifunctional anion exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000471 abnormal stomach epithelium morphology "malformation of the epithelial layer of the stomach " [tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0000473 abnormal stomach glandular epithelium morphology "malformation of the gland-containing epithelial layer of the stomach" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc, J:54637]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0000505 reduced digestive secretion "decrease in the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Slc26a9tm1Sole/Slc26a9+
Genetic Background: involves: 129S/SvEv

 MP:0000507 absent digestive secretion "missing the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004137 abnormal gastric surface mucous cells "malformation of the mucus secreting epithelial cells that lline the luminal surface of the stomach, gastric pits and gastric glands" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004139 abnormal parietal cell morphology "malformation of the gastric acid producing epithelial cells that are distributed throughout the length of the gastric gland " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004140 abnormal chief cell morphology "malformation of the pepsinogen producing epithelial cells that are clustered at the base of the gastric gland " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0008006 increased stomach pH "change in the function of the secretory and buffer systems of the stomach that control the relative acidity or alkalinity, such that the acidity is decreased, as indicated by the decreased concentration of hydrogen ion" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0013566 dilated gastric glands "stretched or widened aperture of the luminal space of any of the branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin" [MGI:Anna]
Show

Allelic Composition: Pdgfratm1Sor/Pdgfra+,Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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