ENSMUSG00000039385


Mus musculus

Features
Gene ID: ENSMUSG00000039385
  
Biological name :Cdh6
  
Synonyms : Cadherin-6 / Cdh6 / P97326
  
Possible biological names infered from orthology : P55285
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: A1
Gene start: 13028701
Gene end: 13173675
  
Corresponding Affymetrix probe sets: 10427862 (MoGene1.0st)   1437558_at (Mouse Genome 430 2.0 Array)   1438989_s_at (Mouse Genome 430 2.0 Array)   1442257_at (Mouse Genome 430 2.0 Array)   1450288_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037113
NCBI entrez gene - 12563     See in Manteia.
MGI - MGI:107435
RefSeq - XM_017316421
RefSeq - NM_007666
RefSeq - XM_006520018
RefSeq - XM_017316420
RefSeq - XM_006520017
RefSeq Peptide - NP_031692
swissprot - P97326
Ensembl - ENSMUSG00000039385
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdh10aENSDARG00000055843Danio rerio
 cdh6ENSDARG00000014522Danio rerio
 LO017650.1ENSDARG00000103903Danio rerio
 CDH6ENSGALG00000012917Gallus gallus
 CDH6ENSG00000113361Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdh10 / P70408 / Cadherin-10 / Q9Y6N8*ENSMUSG0000002232172
Cdh9 / cadherin 9 / Q9ULB4*ENSMUSG0000002537072
Cdh12 / Q5RJH3 / Cadherin-12 / P55289*ENSMUSG0000004045261
Cdh7 / Q8BM92 / Cadherin-7 / Q9ULB5*ENSMUSG0000002631259
Cdh20 / Q9Z0M3 / Cadherin-20 / Q9HBT6*ENSMUSG0000005084058
Cdh11 / P55288 / Cadherin-11 / P55287*ENSMUSG0000003167357
Cdh8 / P97291 / Cadherin-8 / P55286*ENSMUSG0000003651057
Cdh18 / cadherin 18 / Q13634*ENSMUSG0000004042056
Cdh22 / Q9WTP5 / Cadherin-22 / Q9UJ99*ENSMUSG0000005316649
Cdh24 / Q6PFX6 / Cadherin-24 / Q86UP0*ENSMUSG0000005967449
Cdh19 / cadherin 19, type 2 / Q9H159* / cadherin 19*ENSMUSG0000004721644


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007219 Notch signaling pathway IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Iduatm1Clk/Iduatm1Clk
Genetic Background: B6.129-Iduatm1Clk/J

 MP:0011290 decreased nephron number "reduction in the total number of filtering units of the kidney" [MGI:anna]
Show

Allelic Composition: Iduatm1Clk/Iduatm1Clk
Genetic Background: B6.129-Iduatm1Clk/J

 MP:0011291 nephron necrosis "pathologic death of cells within, or a portion of the nephron, usually due to irreversible damage" [MGI:anna]
Show

Allelic Composition: Iduatm1Clk/Iduatm1Clk
Genetic Background: B6.129-Iduatm1Clk/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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