ENSMUSG00000041301


Mus musculus

Features
Gene ID: ENSMUSG00000041301
  
Biological name :Cftr
  
Synonyms : Cftr / Cystic fibrosis transmembrane conductance regulator / P26361
  
Possible biological names infered from orthology : P13569
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A2
Gene start: 18170687
Gene end: 18322768
  
Corresponding Affymetrix probe sets: 10536563 (MoGene1.0st)   1420579_s_at (Mouse Genome 430 2.0 Array)   1427767_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111064
Ensembl peptide - ENSMUSP00000115334
Ensembl peptide - ENSMUSP00000116957
Ensembl peptide - ENSMUSP00000049228
Ensembl peptide - ENSMUSP00000111065
NCBI entrez gene - 12638     See in Manteia.
MGI - MGI:88388
RefSeq - XM_006504979
RefSeq - NM_021050
RefSeq - XM_006504977
RefSeq - XM_006504978
RefSeq Peptide - NP_066388
swissprot - P26361
swissprot - F6U9G7
swissprot - E9PVD7
Ensembl - ENSMUSG00000041301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cftrENSDARG00000041107Danio rerio
 CFTRENSGALG00000032986Gallus gallus
 CFTRENSG00000001626Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*ENSMUSG0000003284930
Abcc2 / Q8VI47 / Canalicular multispecific organic anion transporter 1 / Q92887* / ATP binding cassette subfamily C member 2*ENSMUSG0000002519425
Abcc3 / ATP binding cassette subfamily C member 3 / O15438*ENSMUSG0000002086524
Abcc12 / Q80WJ6 / Multidrug resistance-associated protein 9 / Q96J65* / ATP binding cassette subfamily C member 12*ENSMUSG0000003687224
Abcc5 / Q9R1X5 / Multidrug resistance-associated protein 5 / O15440* / ATP binding cassette subfamily C member 5*ENSMUSG0000002282223
Abcc1 / O35379 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / P33527* / ATP binding cassette subfamily C member 1*ENSMUSG0000002308823
Abcc9 / P70170 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / ATP binding cassette subfamily C member 9*ENSMUSG0000003024923


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR009147  Cystic fibrosis transmembrane conductance regulator
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR025837  CFTR regulator domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036640  ABC transporter type 1, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis IMP
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0030301 cholesterol transport IMP
 biological_processGO:0035377 transepithelial water transport IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0045921 positive regulation of exocytosis IMP
 biological_processGO:0048240 sperm capacitation IMP
 biological_processGO:0050891 multicellular organismal water homeostasis IEA
 biological_processGO:0051454 intracellular pH elevation IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060081 membrane hyperpolarization IMP
 biological_processGO:0071320 cellular response to cAMP IDA
 biological_processGO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity IMP
 biological_processGO:1902476 chloride transmembrane transport IEA
 biological_processGO:1902943 positive regulation of voltage-gated chloride channel activity IEA
 biological_processGO:1904322 cellular response to forskolin IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031205 endoplasmic reticulum Sec complex IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0005260 intracellularly ATP-gated chloride channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity IEA
 molecular_functionGO:0015108 chloride transmembrane transporter activity IMP
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0019869 chloride channel inhibitor activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Ub-specific processing proteases
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: 129P2/OlaHsd

 MP:0000477 abnormal intestine morphology "malformation of the digestive tube passing from the stomach to the anus" [J:48968]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc

 MP:0000490 abnormal crypts of Lieberkuhn morphology "malformation or defects in the tubular intestinal glands found in the mucosal membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cfmq1129X1/SvJ/Cfmq1C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq2129X1/SvJ/Cfmq2129X1/SvJ,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000491 crypt abscesses "an exudate collection associated with inflammation in the crypts of Lieberkuhn of the intestinal mucosa; often associated with ulcerative colitis" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0000494 abnormal cecum morphology "malformation of the large sac at the ileum and large intestine junction" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0000495 abnormal colon morphology "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0000496 abnormal small intestine morphology "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

 MP:0000511 abnormal intestinal mucosa morphology "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0000512 intestinal ulcer "lesions in the mucous lining of the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0000607 abnormal hepatocyte morphology "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0000613 abnormal salivary gland morphology "malformed saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000693 spleen hyperplasia "increased cell number in the spleen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0001135 abnormal cervix morphology "malformation or malfunctioning of the lower opening of the uterus to the vagina" [MGI:tc]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
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Allelic Composition: Npr3lgj-3J/Npr3lgj-3J
Genetic Background: C57BL/6J-Npr3lgj-3J/GrsrJ

 MP:0001177 atelectasis "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cfmq1129X1/SvJ/Cfmq1C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq2129X1/SvJ/Cfmq2129X1/SvJ,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001346 abnormal lacrimal gland morphology "malformation of the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0001438 aphagia "inability to eat " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30404]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Cftrtm2Hgu/Cftrtm2Hgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

Allelic Composition: Cftrtm3Mrc/Cftrtm3Mrc
Genetic Background: B6.129S6-Cftrtm3Mrc

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0001765 abnormal ion homeostasis "anomaly in the state of equilibrium in the body with respect to charged molecules in the fluids and tissues" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001784 abnormal fluid regulation "anomalous control of intracellular and/or extracellular fluid " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001824 abnormal thymic involution "premature or late decline in thymic function normally associated with advancing age" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0001858 intestinal inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Cfmq1129X1/SvJ/Cfmq1C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq2129X1/SvJ/Cfmq2129X1/SvJ,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

Allelic Composition: Cftrtm3Mrc/Cftrtm3Mrc
Genetic Background: B6.129S6-Cftrtm3Mrc

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: 129P2/OlaHsd

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: 129P2/OlaHsd

 MP:0001938 delayed sexual maturation "immaturity of the sexual organs at a given age" [J:61190]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0001944 abnormal pancreas morphology "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001947 abnormal mucociliary clearance "anomaly in the rate of ciliary and secretory activity of the respiratory submucosal glands" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gt(ROSA)26Sortm9(cre/ESR1)Arte/?,Tnfaip3tm1Homy/Tnfaip3tm1Homy
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0002133 abnormal respiratory system physiology "anomalous function of the pulmonary system; inability or reduced ability to intake and exchange oxygen and carbon dioxide with the environment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm2Hgu/Cftrtm2Hgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002163 abnormal gland morphology "abnormal development of any glandular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Cwr/Cftrtm1Cwr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002238 abnormal nasal mucosa morphology "any structural anomaly of the mucous membrane that lines the nasal cavity" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0002240 abnormal paranasal sinus morphology "any structural anomaly of these extensions of the nasal cavity " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0002264 abnormal bronchus morphology "any structural anomaly of of the upper conducting airways of the lung; these airways arise from the terminus of the trachea " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc

 MP:0002282 abnormal trachea morphology "structral anomaly of the tube descending from the larynx and branching into the right and left main bronchi" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0002309 abnormal vital capacity "anomaly in the amount of air that is exhaled by a maximal expiration following a maximal inspiration" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002405 respiratory system inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the respiratory system" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Gt(ROSA)26Sortm9(cre/ESR1)Arte/?,Tnfaip3tm1Homy/Tnfaip3tm1Homy
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

 MP:0002406 increased susceptibility to infection "greater likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Npr3lgj-3J/Npr3lgj-3J
Genetic Background: C57BL/6J-Npr3lgj-3J/GrsrJ

 MP:0002637 small uterus "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: 129P2/OlaHsd

 MP:0002680 decreased number of corpora lutea "fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0002693 abnormal pancreas physiology "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002769 abnormal vas deferens morphology "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

 MP:0002928 abnormal bile duct morphology "malformation of the channels that secrete bile from the liver to the gall bladder and intestines" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0003251 gall bladder inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the gall bladder" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0003270 intestinal obstruction "any impediment, blockage, or reversal of the normal flow of the intestinal contents toward the anus " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Bay/Cftrtm3Bay
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm3Mrc/Cftrtm3Mrc
Genetic Background: B6.129S6-Cftrtm3Mrc

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/1Ztm

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/3Ztm

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0003303 peritoneal inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the membrane that lines the abdominal cavity and covers most of the viscera" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0003340 acute pancreas inflammation "early and often transient reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into the pancreas; initiated by injury, infection, or local immune response " [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003355 reduced ovulation "reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0003426 pulmonary interstitial fibrosis "formation of fibrous tissue within the interstices of the lung as a result of repair or a reactive process" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:63134]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc

 MP:0003449 abnormal intestinal goblet cells "malformation of the unicellular mucin-secreting glands" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95282]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm2Hgu/Cftrtm2Hgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: B6.129P2-Cftrtm1Eur

 MP:0003666 impaired sperm capacitation "anomaly in the change undergone by spermatozoa in the female genital tract that enables them to penetrate and fertilize an egg" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96669]
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Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: 129P2/OlaHsd

 MP:0003793 abnormal submandibular gland morphology "any structural malformation of either of the large major salivary glands situated beneath the mandible" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0004002 abnormal jejunum morphology "malformation of the portion of the small intestine that extends from the duodenum to the ileum" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Wwtr1tm1Hku/Wwtr1tm1Hku
Genetic Background: involves: 129 * C57BL/6 * ICR

Allelic Composition: Cftrtm1Unc/Cftr+
Genetic Background: involves: BALB/cJ * C57BL/6J

 MP:0004247 small pancreas "decrease of the size of the pancreas compared to controls" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0004777 abnormal phospholipid level "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

 MP:0004841 abnormal small intestine crypts of Lieberkuhn morphology "any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the small intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: B6.129P2-Cftrtm1Eur

 MP:0004842 abnormal large intestine crypts of Lieberkuhn morphology "any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the large intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0004905 decreased uterus weight "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0005084 abnormal gall bladder morphology "anomalous structure or development of the organ which serves as a storage reservoir for bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0005085 abnormal gall bladder physiology "anomalous action or function of the organ that stores and concentrates bile " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0008245 abnormal alveolar macrophage morphology "any structural anomaly of the round, granular, mononuclear phagocytes found in the alveoli of the lungs which ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells" [CL:0000583, MESH:A.11.329.372.600]
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Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Slc9a3r1tm1Ssl/Slc9a3r1tm1Ssl
Genetic Background: FVB.129-Slc9a3r1tm1Ssl

 MP:0009006 prolonged estrous cycle "increase in the length of the sexual cycle of female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0009009 absent estrous cycle "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0009081 thin uterus "reduced thickness or depth of the female muscular organ of gestation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

 MP:0009144 dilated pancreatic duct "an increase in volume of the luminal space of the excretory duct of the exocrine pancreas that collects fluid containing digestive enzymes and transports it to the duodenum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A03.734.667]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

 MP:0009150 pancreatic acinar cell atrophy "wasting of the pancreatic acinar cells due to injury or disease, resulting in reduced size or number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0009161 pancreatic acinar cell zymogen granule accumulation "a gradually increasing number of membrane-bounded, cytoplasmic secretory granules found in pancreatic acinar cells that contain inactive digestive enzyme precursors" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

 MP:0009342 enlarged gall bladder "increased size of the gall bladder, the organ that serves as a storage reservoir for bile" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0009343 dilated gall bladder "abnormal distention of the gall bladder due to accumulation of fluid or bile" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0009477 small cecum "reduced size of the large sac at the ileum and large intestine junction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

 MP:0009478 coiled cecum "corkscrew or worm-like appearance of the large sac at the ileum and large intestine junction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0009484 ileum hypertrophy "an increase in the bulk size of the portion of the small intestine that extends from the jejunum to the colon due to cell enlargement" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

Allelic Composition: Cftrtm3Mrc/Cftrtm3Mrc
Genetic Background: B6.129S6-Cftrtm3Mrc

 MP:0010155 abnormal intestine physiology "any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J * DBA/2J

 MP:0010156 abnormal small intestinal crypt cell physiology "altered function of the cells that make up the tubular intestinal glands found in the mucosal membranes of the small intestine" [MGI:jbubier "Jason Bubier, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: B6.129P2-Cftrtm1Eur

 MP:0010831 partial lethality "the appearance of lower than Mendelian ratios of offspring of a given genotype due to death of some, but not all of the organisms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/1Ztm

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/3Ztm

 MP:0010858 pulmonary epithelial necrosis "pathological cell death in the lung epithelium, usually due to irreversible damage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm9(cre/ESR1)Arte/?,Tnfaip3tm1Homy/Tnfaip3tm1Homy
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac

 MP:0010861 increased respiratory mucosa goblet cell number "greater number of the cells of the respiratory epithelial lining that produce and secrete mucins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0010895 increased lung compliance "increased ability of the lung to distend in response to pressure without disruption, usually expressed as the unit volume of change in the lung per unit of pressure" [ISBN:070202788 "Saunders Comprehensive Veterinary Dictionary, 3rd edition"]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Clec16atm1.1Hhak/Clec16atm1.1Hhak,Tg(Pdx1-cre)1Herr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA/J * SJL

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc,Tg(FABPCFTR)1Jaw/0,Tg(Scgb1a1-Scnn1b)6608Bouc/0
Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6 * FVB/N

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J * DBA/2J

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cftrtm2Hgu/Cftrtm2Hgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0012518 abnormal Brunner s gland morphology "any structural anomaly of the branched acinotubular glands found in the submucosa of the duodenum located above the Sphincter of Oddi; their main function is to produce a mucus-rich alkaline secretion (containing bicarbonate) to protect the duodenum from the acidic content of chyme, provide an alkaline condition for the intestinal enzymes to be active (thus enabling absorption to take place), and lubricate the intestinal walls; they also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes" [MGI:anna]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0012519 dilated Brunner s glands "stretched or widened aperture of the luminal space of the branched acinotubular glands found in the submucosa of the duodenum located above the Sphincter of Oddi; their main function is to produce a mucus-rich alkaline secretion (containing bicarbonate) to protect the duodenum from the acidic content of chyme, provide an alkaline condition for the intestinal enzymes to be active (thus enabling absorption to take place), and lubricate the intestinal walls; they also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes" [MGI:anna]
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Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0013455 lacrimal gland atrophy "acquired diminution of the size of any of the paired glands that secrete the aqueous layer of the tear film, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna]
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Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0013494 abnormal trachea gland morphology "any structural anomaly of the tubuloacinar seromucous glands located principally in the submucosa of the trachea whose excretory ducts pass through the lamina propria to the tracheal lumen; they secrete mucus, lysozyme, defensins, and other agents that help protect the lungs from particles and infectious agents; in the mouse, they are restricted to the upper trachea, more specifically to the regions between the first few cartilage rings, with the precise distribution depending on genetic background" [http://medical-dictionary.thefreedictionary.com/tracheal+glands, ISBN:1451113412, MGI:Anna, PMID:15973734]
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd

 MP:0013792 abnormal small intestine goblet cell morphology "any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the small intestine, whose primary function is to secrete gel-forming mucins, the major components of mucus" [MGI:Anna, PMID:25872481]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0013795 abnormal colon goblet cell morphology "any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the colon, whose primary function is to secrete gel-forming mucins, the major components of mucus" [MGI:Anna, PMID:25872481]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc,Tg(FABPCFTR)1Jaw/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0013797 abnormal ileal goblet cell morphology "any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the ileum of the small intestine, whose primary function is to secrete gel-forming mucins, the major components of mucus" [PMID:25872481]
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Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/1Ztm

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: CF/3Ztm

 MP:0014028 decreased respiratory epithelial chloride transmembrane transport "decrease in the directed movement of a chloride from one side of the respiratory epithelial cell membrane to the other" [MGI:csmith]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Kth/Cftrtm1Kth
Genetic Background: B6.129S7-Cftrtm1Kth

Allelic Composition: Cftrtm2Mrc/Cftrtm2Mrc
Genetic Background: B6.129S6-Cftrtm2Mrc

Allelic Composition: Cftrtm3Mrc/Cftrtm3Mrc
Genetic Background: B6.129S6-Cftrtm3Mrc

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0014033 abnormal submucosal gland morphology "any functional anomaly of the mucous-secreting glands located in the dense irregular connective tissue that lines organs and supports the mucosal membrane" [ISBN:0683400088, MGI:csmith]
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0014036 meconium ileus "obstruction of the intestine due to abnormally thick meconium in the fetus and neonate" [ISBN:0683400088]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

Allelic Composition: Cftrtm2Cam/Cftrtm2Cam
Genetic Background: involves: 129S/SvEv

Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0014079 decreased small intestinal villus number "fewer than normal numbers of the tiny hair-like projections which protrude from the inside of the small intestine and contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall" [MGI:Anna, PMID:16679353]
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0014182 decreased respiratory epithelial sodium ion transmembrane transport "decrease in the directed movement of sodium ions from one side of the respiratory epithelial cell membrane to the other" [MGI:csmith]
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0014183 increased repiratory epitheliam sodium ion transmembrane transport "increase in the directed movement of sodium ion from one side of the respiratory epithelial cell membrane to the other" [MGI:csmith]
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Allelic Composition: Cftrtm1Hsc/Cftrtm1Hsc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0014206 decreased intestinal epithelial sodium ion transmembrane transport 
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

 MP:0014208 decreased intestinal epithelial chloride transmembrane transport 
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Allelic Composition: Cftrtm1Hgu/Cftrtm1Hgu
Genetic Background: involves: 129P2/OlaHsd * MF1

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc,Tg(FABPCFTR)1Jaw/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Cftrtm1Eur/Cftrtm1Eur
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0014226 abnormal alveolar macrophage physiology 
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc,Tg(FABPCFTR)1Jaw/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0014230 dilated crypts of Lieberkuhn 
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0014231 intestinal mucus accumulation 
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Allelic Composition: Foxa2tm1Khk/Foxa2tm1Khk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA

Allelic Composition: Cftrtm1Bay/Cftrtm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Cftrtm1.1Cwr/Cftrtm1.1Cwr
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

 MP:0014232 pancreatic acinus dilation 
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc
Genetic Background: B6.129P2-Cftrtm1Unc/J

 MP:0014233 bile duct epithelium hyperplasia 
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Allelic Composition: Cftrtm3Hgu/Cftrtm3Hgu
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031826 Usp10 / P52479 / ubiquitin specific peptidase 10 / Q14694*  / complex






 

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