Manteia

ENSMUSG00000043468

Mus musculus

Features

Gene ID:	ENSMUSG00000043468

Biological name :	Adam30

Synonyms :	Adam30 / a disintegrin and metallopeptidase domain 30

Possible biological names infered from orthology :	ADAM metallopeptidase domain 30 / Q9UKF2

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	F2.2
Gene start:	98160630
Gene end:	98164169

Corresponding Affymetrix probe sets:	10494632 (MoGene1.0st)

Cross references:	Ensembl peptide - ENSMUSP00000060505 Ensembl peptide - ENSMUSP00000142590 NCBI entrez gene - 71078 See in Manteia. MGI - MGI:1918328 RefSeq - NM_027665 RefSeq Peptide - NP_081941 swissprot - Q811Q3 swissprot - Q9CUC4 Ensembl - ENSMUSG00000043468

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
zgc:174164	ENSDARG00000057138	Danio rerio
	ENSGALG00000013838	Gallus gallus
ADAM30	ENSG00000134249	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Adam9 / Q61072 / Disintegrin and metalloproteinase domain-containing protein 9 / Q13443* / ADAM metallopeptidase domain 9*	ENSMUSG00000031555	34
Adam29 / ADAM metallopeptidase domain 29 / Q9UKF5*	ENSMUSG00000046258	34
Adam26b / a disintegrin and metallopeptidase domain 26B	ENSMUSG00000063900	34
Adam21 / Q9JI76 / Disintegrin and metalloproteinase domain-containing protein 21 / Q9UKJ8* / ADAM metallopeptidase domain 21*	ENSMUSG00000008438	33
Adam25	ENSMUSG00000071937	33
Adam34 / a disintegrin and metallopeptidase domain 34	ENSMUSG00000079058	33
Adam20 / a disintegrin and metallopeptidase domain 20	ENSMUSG00000046282	32
Adam24 / Q9R160 / Disintegrin and metalloproteinase domain-containing protein 24	ENSMUSG00000046723	32
Q9R158 / Adam26a / Disintegrin and metalloproteinase domain-containing protein 26A	ENSMUSG00000048516	32
Gm5346	ENSMUSG00000050190	32
Adam39 / a disintegrin and metallopeptidase domain 39	ENSMUSG00000054033	32
Adam1b / Q8R534 / Disintegrin and metalloproteinase domain-containing protein 1b	ENSMUSG00000062438	31
Adam1a / O54992 / Q60813 / Disintegrin and metalloproteinase domain-containing protein 1a	ENSMUSG00000072647	31
Adam6a / a disintegrin and metallopeptidase domain 6A	ENSMUSG00000043945	29
Adam2 / Q60718 / Disintegrin and metalloproteinase domain-containing protein 2 / Q99965* / ADAM metallopeptidase domain 2*	ENSMUSG00000022039	28
Adam6b / a disintegrin and metallopeptidase domain 6B	ENSMUSG00000051804	28
Adam4 / a disintegrin and metallopeptidase domain 4	ENSMUSG00000072972	28
Gm4787	ENSMUSG00000072974	28
Adam32 / Q8K410 / Disintegrin and metalloproteinase domain-containing protein 32 / Q8TC27* / ADAM metallopeptidase domain 32*	ENSMUSG00000037437	26
Adam18 / Q9R157 / Disintegrin and metalloproteinase domain-containing protein 18 / Q9Y3Q7* / ADAM metallopeptidase domain 18*	ENSMUSG00000031552	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR000742	EGF-like domain
IPR001590	Peptidase M12B, ADAM/reprolysin
IPR001762	Disintegrin domain
IPR002870	Peptidase M12B, propeptide
IPR006586	ADAM, cysteine-rich
IPR013032	EGF-like, conserved site
IPR018358	Disintegrin, conserved site
IPR024079	Metallopeptidase, catalytic domain superfamily
IPR034027	Reprolysin domain, adamalysin-type
IPR036436	Disintegrin domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006508	proteolysis	IEA
biological_process	GO:0007229	integrin-mediated signaling pathway	IEA
biological_process	GO:0008150	biological_process	ND
cellular_component	GO:0009897	external side of plasma membrane	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:1990913	sperm head plasma membrane	IDA
molecular_function	GO:0003674	molecular_function	ND
molecular_function	GO:0004222	metalloendopeptidase activity	IEA
molecular_function	GO:0008237	metallopeptidase activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Interaction With The Zona Pellucida

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000008438	Adam21 / Q9JI76 / Disintegrin and metalloproteinase domain-containing protein 21 / Q9UKJ8* / ADAM metallopeptidase domain 21*	/ complex
ENSMUSG00000028413	P15535 / B4galt1 / Beta-1,4-galactosyltransferase 1 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetyl...	/ complex / reaction
ENSMUSG00000022039	Adam2 / Q60718 / Disintegrin and metalloproteinase domain-containing protein 2 / Q99965* / ADAM metallopeptidase domain 2*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr