ENSMUSG00000050190


Mus musculus
domainGm5346disintegrinpeptidasembadamreprolysinmetallopeptidasesuperfamilycomponentmembraneactivityegf-likepropeptidecysteine-richconservedsitecatalyticadamalysin-typeproteolysisbiologicalprocesscellularintegralmolecularfunctionmetalloendopeptidasemetalionbinding

Features
Gene ID: ENSMUSG00000050190
  
Biological name :Gm5346
  
Synonyms : Gm5346
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A4
Gene start: 43624951
Gene end: 43627276
  
Corresponding Affymetrix probe sets: 10578413 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000058858
NCBI entrez gene - 384813     See in Manteia.
MGI - MGI:3647273
RefSeq - NM_001025240
RefSeq - XM_006509455
RefSeq Peptide - NP_001020411
swissprot - Q7M766
Ensembl - ENSMUSG00000050190
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:174164ENSDARG00000057138Danio rerio
 ENSGALG00000013838Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adam34 / a disintegrin and metallopeptidase domain 34ENSMUSG0000007905885
Q9R158 / Adam26a / Disintegrin and metalloproteinase domain-containing protein 26A ENSMUSG0000004851674
Adam26b / a disintegrin and metallopeptidase domain 26BENSMUSG0000006390074
Adam25ENSMUSG0000007193747
Adam20 / a disintegrin and metallopeptidase domain 20ENSMUSG0000004628246
Adam24 / Q9R160 / Disintegrin and metalloproteinase domain-containing protein 24 ENSMUSG0000004672346
Adam39 / a disintegrin and metallopeptidase domain 39ENSMUSG0000005403346
Adam29 / ADAM metallopeptidase domain 29 / Q9UKF5*ENSMUSG0000004625842
Adam21 / Q9JI76 / Disintegrin and metalloproteinase domain-containing protein 21 / Q9UKJ8* / ADAM metallopeptidase domain 21*ENSMUSG0000000843840
Adam9 / Q61072 / Disintegrin and metalloproteinase domain-containing protein 9 / Q13443* / ADAM metallopeptidase domain 9*ENSMUSG0000003155535
Adam1a / O54992 / Q60813 / Disintegrin and metalloproteinase domain-containing protein 1a ENSMUSG0000007264733
Adam30 / a disintegrin and metallopeptidase domain 30 / Q9UKF2* / ADAM metallopeptidase domain 30*ENSMUSG0000004346831
Adam1b / Q8R534 / Disintegrin and metalloproteinase domain-containing protein 1b ENSMUSG0000006243831
Adam6a / a disintegrin and metallopeptidase domain 6AENSMUSG0000004394530
Adam6b / a disintegrin and metallopeptidase domain 6BENSMUSG0000005180430
Adam4 / a disintegrin and metallopeptidase domain 4ENSMUSG0000007297229
Adam2 / Q60718 / Disintegrin and metalloproteinase domain-containing protein 2 / Q99965* / ADAM metallopeptidase domain 2*ENSMUSG0000002203928
Gm4787ENSMUSG0000007297427
Adam32 / Q8K410 / Disintegrin and metalloproteinase domain-containing protein 32 / Q8TC27* / ADAM metallopeptidase domain 32*ENSMUSG0000003743726
Adam18 / Q9R157 / Disintegrin and metalloproteinase domain-containing protein 18 / Q9Y3Q7* / ADAM metallopeptidase domain 18*ENSMUSG0000003155224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processnitrogen compound metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic processorganic substance metabolic process
catalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activityion bindingion binding
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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