ENSMUSG00000069094


Mus musculus

Features
Gene ID: ENSMUSG00000069094
  
Biological name :Pde7a
  
Synonyms : High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A / P70453 / Pde7a
  
Possible biological names infered from orthology : phosphodiesterase 7A / Q13946
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A2
Gene start: 19223108
Gene end: 19311322
  
Corresponding Affymetrix probe sets: 10497399 (MoGene1.0st)   1423313_at (Mouse Genome 430 2.0 Array)   1423314_s_at (Mouse Genome 430 2.0 Array)   1438041_at (Mouse Genome 430 2.0 Array)   1439484_at (Mouse Genome 430 2.0 Array)   1450933_at (Mouse Genome 430 2.0 Array)   1451839_a_at (Mouse Genome 430 2.0 Array)   1458218_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088863
Ensembl peptide - ENSMUSP00000113173
Ensembl peptide - ENSMUSP00000119685
Ensembl peptide - ENSMUSP00000120420
Ensembl peptide - ENSMUSP00000096800
NCBI entrez gene - 18583     See in Manteia.
MGI - MGI:1202402
RefSeq - XM_011249666
RefSeq - NM_001122759
RefSeq - NM_008802
RefSeq - XM_006535405
RefSeq - XM_006535406
RefSeq - XM_006535408
RefSeq Peptide - NP_032828
RefSeq Peptide - NP_001116231
swissprot - F6VJY9
swissprot - Q3U3Y7
swissprot - D3Z6W6
swissprot - D6RIM5
swissprot - P70453
Ensembl - ENSMUSG00000069094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde7aENSDARG00000045305Danio rerio
 PDE7AENSGALG00000038395Gallus gallus
 PDE7AENSG00000205268Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pde7b / Q9QXQ1 / cAMP-specific 3,5-cyclic phosphodiesterase 7B / Q9NP56* / phosphodiesterase 7B*ENSMUSG0000001999056
Pde4a / O89084 / phosphodiesterase 4A, cAMP specific / P27815* / phosphodiesterase 4A*ENSMUSG0000003217731
Pde4d / Q01063 / cAMP-specific 3,5-cyclic phosphodiesterase 4D / Q08499* / phosphodiesterase 4D*ENSMUSG0000002169929
Pde4b / phosphodiesterase 4B, cAMP specific / Q07343* / phosphodiesterase 4B*ENSMUSG0000002852529
Pde4c / Q3UEI1 / cAMP-specific 3,5-cyclic phosphodiesterase 4C / Q08493* / AC008397.2* / phosphodiesterase 4C*ENSMUSG0000003184229
Pde8a / O88502 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A / O60658* / phosphodiesterase 8A*ENSMUSG0000002558426
Pde8b / E9Q4S1 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B / O95263* / AC022414.1* / phosphodiesterase 8B* / high affinity cAMP-specific and IBMX-ins...ENSMUSG0000002168424
Pde1c / Q64338 / phosphodiesterase 1C / Q14123*ENSMUSG0000000434723
Pde1b / Q01065 / Calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B / Q01064* / phosphodiesterase 1B*ENSMUSG0000002248923
Pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSMUSG0000005917323


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity ISO
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Gata3tm1Iho/Gata3tm1Iho,Tg(Cd4-cre)1Cwi/0
Genetic Background: involves: C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr