ENSMUSG00000094652


Mus musculus

Features
Gene ID: ENSMUSG00000094652
  
Biological name :Ighv1-42
  
Synonyms : Ighv1-42
  
Possible biological names infered from orthology : A0A0A0MS14 / A0A0C4DH29 / A0A0C4DH31 / A0A0C4DH39 / AC135068.8 / IGHV1-18 / IGHV1-2 / IGHV1-3 / IGHV1-45 / IGHV1-58 / IGHV1OR15-1 / immunoglobulin heavy variable 1-18 / immunoglobulin heavy variable 1-2 / immunoglobulin heavy variable 1-3 / immunoglobulin heavy variable 1-45 / immunoglobulin heavy variable 1-58 / immunoglobulin heavy variable 1/OR15-1 (non-functional) / P23083
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F2
Gene start: 114937113
Gene end: 114937544
  
Corresponding Affymetrix probe sets: 10403021 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000100297
Ensembl peptide - ENSMUSP00000142261
MGI - MGI:3704123
swissprot - A0A075B5V6
swissprot - A0A0A6YY38
Ensembl - ENSMUSG00000094652
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ighv1-2ENSDARG00000096350Danio rerio
 ighv2-1ENSDARG00000096406Danio rerio
 ighv2-2ENSDARG00000096424Danio rerio
 ighv2-3ENSDARG00000096376Danio rerio
 AC135068.8ENSG00000281179Homo sapiens
 IGHV1-18ENSG00000211945Homo sapiens
 IGHV1-3ENSG00000211935Homo sapiens
 IGHV1-45ENSG00000211961Homo sapiens
 IGHV1-58ENSG00000211968Homo sapiens
 IGHV1OR15-1ENSG00000270505Homo sapiens
 P23083ENSG00000211934Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ighv1-26 / immunoglobulin heavy variable 1-26 / P23083* / IGHV1-2* / IGHV1-3* / IGHV1-45* / IGHV1-18* / IGHV1-58* / AC135068.8* / A0A0A0MS14* / A0A0C4DH29* / A0A0C4DH31* / A0A0C4DH39* / IGH...ENSMUSG0000009454685
Ighv1-19 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0C4DH39* / A0A0C4DH31* / A0A0A0MS14* / A0A0C4DH29* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009641084
Ighv1-34 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0C4DH39* / A0A0C4DH31* / A0A0A0MS14* / A0A0C4DH29* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009395581
Ighv1-22 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0C4DH39* / A0A0C4DH31* / A0A0A0MS14* / A0A0C4DH29* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009456181
Ighv1-66 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009551978
Ighv1-75 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009602078
Ighv1-84 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009494077
Ighv1-4 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0C4DH39* / A0A0C4DH31* / A0A0A0MS14* / A0A0C4DH29* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy varia...ENSMUSG0000009544277
Ighv1-53 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0A0MS14* / AC135068.8* / A0A0C4DH31* / A0A0C4DH29* / A0A0C4DH39* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009389476
Ighv1-7 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy varia...ENSMUSG0000009520076
Ighv1-85 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009615076
Ighv1-12 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0C4DH39* / A0A0C4DH31* / A0A0A0MS14* / A0A0C4DH29* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009541675
Ighv1-77 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009645275
Ighv1-64 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009408874
Ighv1-50 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0A0MS14* / AC135068.8* / A0A0C4DH31* / A0A0C4DH29* / A0A0C4DH39* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009419874
Ighv1-69 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009450274
Ighv1-54 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0A0MS14* / AC135068.8* / A0A0C4DH31* / A0A0C4DH29* / A0A0C4DH39* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009478774
Ighv1-56 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-45* / IGHV1-18* / IGHV1-58* / A0A0A0MS14* / AC135068.8* / A0A0C4DH31* / A0A0C4DH29* / A0A0C4DH39* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009486274
Ighv1-72 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009607474
Ighv1-76 / P23083* / IGHV1-3* / IGHV1-2* / IGHV1-58* / IGHV1-18* / IGHV1-45* / A0A0C4DH39* / A0A0C4DH29* / A0A0A0MS14* / A0A0C4DH31* / AC135068.8* / IGHV1OR15-1* / immunoglobulin heavy vari...ENSMUSG0000009389673


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
Cell surface interactions at the vascular wall
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Scavenging of heme from plasma
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
CD22 mediated BCR regulation
Regulation of Complement cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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