ENSG00000211961


Homo sapiens
immuneresponsemembraneIGHV1-45phagocytosisactivationpathwaybcellreceptorplasmaimmunoglobulinbindingadaptiveprocessrecognitionengulfmentcomplementclassicaldefensebacteriuminnatesignalingregulationextracellularregionexternalsidecomplexcirculatingblood

Features
Gene ID: ENSG00000211961
  
Biological name :IGHV1-45
  
Synonyms : A0A0A0MS14 / IGHV1-45 / immunoglobulin heavy variable 1-45
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.33
Gene start: 106506996
Gene end: 106507491
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000375030
swissprot - A0A0A0MS14
Ensembl - ENSG00000211961
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ighv1-2ENSDARG00000096350Danio rerio
 ighv2-1ENSDARG00000096406Danio rerio
 ighv2-2ENSDARG00000096424Danio rerio
 ighv2-3ENSDARG00000096376Danio rerio
 Ighv1-11ENSMUSG00000102888Mus musculus
 Ighv1-12ENSMUSG00000095416Mus musculus
 Ighv1-19ENSMUSG00000096410Mus musculus
 Ighv1-22ENSMUSG00000094561Mus musculus
 Ighv1-26ENSMUSG00000094546Mus musculus
 Ighv1-34ENSMUSG00000093955Mus musculus
 Ighv1-4ENSMUSG00000095442Mus musculus
 Ighv1-42ENSMUSG00000094652Mus musculus
 Ighv1-5ENSMUSG00000096499Mus musculus
 Ighv1-50ENSMUSG00000094198Mus musculus
 Ighv1-52ENSMUSG00000095204Mus musculus
 Ighv1-53ENSMUSG00000093894Mus musculus
 Ighv1-54ENSMUSG00000094787Mus musculus
 Ighv1-55ENSMUSG00000095589Mus musculus
 Ighv1-56ENSMUSG00000094862Mus musculus
 Ighv1-62-1ENSMUSG00000102313Mus musculus
 Ighv1-63ENSMUSG00000096672Mus musculus
 Ighv1-64ENSMUSG00000094088Mus musculus
 Ighv1-66ENSMUSG00000095519Mus musculus
 Ighv1-69ENSMUSG00000094502Mus musculus
 Ighv1-7ENSMUSG00000095200Mus musculus
 Ighv1-72ENSMUSG00000096074Mus musculus
 Ighv1-74ENSMUSG00000094124Mus musculus
 Ighv1-75ENSMUSG00000096020Mus musculus
 Ighv1-76ENSMUSG00000093896Mus musculus
 Ighv1-77ENSMUSG00000096452Mus musculus
 Ighv1-84ENSMUSG00000094940Mus musculus
 Ighv1-85ENSMUSG00000096150Mus musculus
 Ighv1-9ENSMUSG00000094694Mus musculus
 P01749ENSMUSG00000094087Mus musculus
 P01754ENSMUSG00000096767Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGHV1-3 / A0A0C4DH29 / immunoglobulin heavy variable 1-3ENSG0000021193583
P23083 / IGHV1-2 / immunoglobulin heavy variable 1-2ENSG0000021193481
IGHV1OR15-1 / immunoglobulin heavy variable 1/OR15-1 (non-functional)ENSG0000027050580
AC135068.8ENSG0000028117980
IGHV1-18 / A0A0C4DH31 / immunoglobulin heavy variable 1-18ENSG0000021194579
IGHV1-58 / A0A0C4DH39 / immunoglobulin heavy variable 1-58ENSG0000021196878
P01742 / IGHV1-69 / immunoglobulin heavy variable 1-69ENSG0000021197377
IGHV1-69D / A0A0B4J2H0 / immunoglobulin heavy variable 1-69DENSG0000028041177
P01743 / IGHV1-46 / immunoglobulin heavy variable 1-46ENSG0000021196276
IGHV1OR21-1 / immunoglobulin heavy variable 1/OR21-1 (non-functional)ENSG0000027728274
IGHV1OR15-9 / immunoglobulin heavy variable 1/OR15-9 (non-functional)ENSG0000018840373
IGHV1-24 / A0A0C4DH33 / immunoglobulin heavy variable 1-24ENSG0000021195073
A0A0G2JMI3 / IGHV1-69-2 / immunoglobulin heavy variable 1-69-2ENSG0000028199070
IGHV7-4-1 / A0A0J9YVY3 / immunoglobulin heavy variable 7-4-1ENSG0000028212268
IGHV7-81 / immunoglobulin heavy variable 7-81 (non-functional)ENSG0000021197966
IGHV5-51 / A0A0C4DH38 / immunoglobulin heavy variable 5-51ENSG0000021196655
A0A0J9YXX1 / IGHV5-10-1 / immunoglobulin heavy variable 5-10-1ENSG0000028265155


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
immune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune resimmune responsecell recogcell recognitionestablishmestablishment of localizationcellular ccellular component organizationnitrogen cnitrogen compound metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processimmune effimmune effector processresponse tresponse to stressresponse tresponse to external stimulusresponse tresponse to biotic stimuluscell commucell communicationcellular rcellular response to stimuluscell activcell activation
antigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingantigen bindingprotein bindingprotein binding
extracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regionextracellular regioncellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr