ENSDARG00000096424


Danio rerio

Features
Gene ID: ENSDARG00000096424
  
Biological name :ighv2-2
  
Synonyms : ighv2-2 / immunoglobulin heavy variable 2-2
  
Possible biological names infered from orthology : A0A0A0MS14 / A0A0B4J2H0 / A0A0C4DH29 / A0A0C4DH31 / A0A0C4DH33 / A0A0C4DH38 / A0A0C4DH39 / A0A0G2JMI3 / A0A0J9YVY3 / A0A0J9YXX1 / AC135068.8 / Ig heavy chain V region 1-62-3 / Ig heavy chain V region 3 / Ighv1-11 / Ighv1-12 / IGHV1-18 / Ighv1-19 / IGHV1-2 / Ighv1-22 / IGHV1-24 / Ighv1-26 / IGHV1-3 / Ighv1-34 / Ighv1-4 / Ighv1-42 / IGHV1-45 / IGHV1-46 / Ighv1-5 / Ighv1-50 / Ighv1-52 / Ighv1-53 / Ighv1-54 / Ighv1-55 / Ighv1-56 / IGHV1-58 / Ighv1-61 / Ighv1-62-1 / Ighv1-62-3 / Ighv1-63 / Ighv1-64 / Ighv1-66 / IGHV1-69 / IGHV1-69-2 / IGHV1-69D / Ighv1-7 / Ighv1-72 / Ighv1-74 / Ighv1-75 / Ighv1-76 / Ighv1-77 / Ighv1-84 / Ighv1-85 / Ighv1-9 / IGHV1OR15-1 / IGHV1OR15-9 / IGHV1OR21-1 / IGHV5-10-1 / IGHV5-51 / IGHV7-4-1 / IGHV7-81 / Ighv9-1 / Ighv9-2 / Ighv9-3 / Ighv9-4 / immunoglobulin heavy variable 1-18 / immunoglobulin heavy variable 1-2 / immunoglobulin heavy variable 1-24 / immunoglobulin heavy variable 1-26 / immunoglobulin heavy variable 1-3 / immunoglobulin heavy variable 1-45 / immunoglobulin heavy variable 1-46 / immunoglobulin heavy variable 1-58 / immunoglobulin heavy variable 1-69 / immunoglobulin heavy variable 1-69-2 / immunoglobulin heavy variable 1-69D / immunoglobulin heavy variable 1/OR15-1 (non-functional) / immunoglobulin heavy variable 1/OR15-9 (non-functional) / immunoglobulin heavy variable 1/OR21-1 (non-functional) / immunoglobulin heavy variable 5-10-1 / immunoglobulin heavy variable 5-51 / immunoglobulin heavy variable 7-4-1 / immunoglobulin heavy variable 7-81 (non-functional) / P01742 / P01743 / P01749 / P01754 / P23083
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 34055269
Gene end: 34055745
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126004
swissprot - M9MMF1
ZFIN ID - ZDB-GENE-030924-5
Ensembl - ENSDARG00000096424
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A0A0G2JMI3ENSG00000281990Homo sapiens
 A0A0J9YXX1ENSG00000282651Homo sapiens
 AC135068.8ENSG00000281179Homo sapiens
 IGHV1-18ENSG00000211945Homo sapiens
 IGHV1-24ENSG00000211950Homo sapiens
 IGHV1-3ENSG00000211935Homo sapiens
 IGHV1-45ENSG00000211961Homo sapiens
 IGHV1-58ENSG00000211968Homo sapiens
 IGHV1-69DENSG00000280411Homo sapiens
 IGHV1OR15-1ENSG00000270505Homo sapiens
 IGHV1OR15-9ENSG00000188403Homo sapiens
 IGHV1OR21-1ENSG00000277282Homo sapiens
 IGHV5-51ENSG00000211966Homo sapiens
 IGHV7-4-1ENSG00000282122Homo sapiens
 IGHV7-81ENSG00000211979Homo sapiens
 P01742ENSG00000211973Homo sapiens
 P01743ENSG00000211962Homo sapiens
 P23083ENSG00000211934Homo sapiens
 Ighv1-11ENSMUSG00000102888Mus musculus
 Ighv1-12ENSMUSG00000095416Mus musculus
 Ighv1-19ENSMUSG00000096410Mus musculus
 Ighv1-22ENSMUSG00000094561Mus musculus
 Ighv1-26ENSMUSG00000094546Mus musculus
 Ighv1-34ENSMUSG00000093955Mus musculus
 Ighv1-4ENSMUSG00000095442Mus musculus
 Ighv1-42ENSMUSG00000094652Mus musculus
 Ighv1-5ENSMUSG00000096499Mus musculus
 Ighv1-50ENSMUSG00000094198Mus musculus
 Ighv1-52ENSMUSG00000095204Mus musculus
 Ighv1-53ENSMUSG00000093894Mus musculus
 Ighv1-54ENSMUSG00000094787Mus musculus
 Ighv1-55ENSMUSG00000095589Mus musculus
 Ighv1-56ENSMUSG00000094862Mus musculus
 Ighv1-62-1ENSMUSG00000102313Mus musculus
 Ighv1-63ENSMUSG00000096672Mus musculus
 Ighv1-64ENSMUSG00000094088Mus musculus
 Ighv1-66ENSMUSG00000095519Mus musculus
 Ighv1-69ENSMUSG00000094502Mus musculus
 Ighv1-7ENSMUSG00000095200Mus musculus
 Ighv1-72ENSMUSG00000096074Mus musculus
 Ighv1-74ENSMUSG00000094124Mus musculus
 Ighv1-75ENSMUSG00000096020Mus musculus
 Ighv1-76ENSMUSG00000093896Mus musculus
 Ighv1-77ENSMUSG00000096452Mus musculus
 Ighv1-84ENSMUSG00000094940Mus musculus
 Ighv1-85ENSMUSG00000096150Mus musculus
 Ighv1-9ENSMUSG00000094694Mus musculus
 Ighv9-1ENSMUSG00000096805Mus musculus
 Ighv9-2ENSMUSG00000094102Mus musculus
 Ighv9-3ENSMUSG00000096459Mus musculus
 Ighv9-4ENSMUSG00000094322Mus musculus
 P01749ENSMUSG00000094087Mus musculus
 P01754ENSMUSG00000096767Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ighv2-1 / immunoglobulin heavy variable 2-1 / P01749* / P01743* / P01742* / P23083* / P01754* / Ighv1-9* / Ighv1-7* / IGHV1-2* / Ighv9-4* / IGHV1-3* / Ighv9-3* / Ighv1-4* / Ighv9-2* / Ighv9...ENSDARG0000009640688
ighv2-3 / immunoglobulin heavy variable 2-3 / P01749* / P01743* / P01742* / P23083* / P01754* / Ighv1-9* / Ighv1-7* / IGHV1-2* / Ighv9-4* / IGHV1-3* / Ighv9-3* / Ighv1-4* / Ighv9-2* / Ighv9...ENSDARG0000009637673
ighv1-2 / immunoglobulin heavy variable 1-2 / P01742* / P23083* / P01754* / P01749* / P01743* / Ighv1-4* / Ighv9-3* / Ighv1-7* / Ighv9-4* / Ighv1-5* / Ighv9-2* / Ighv1-9* / IGHV1-3* / Ighv9...ENSDARG0000009635053


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Regulation of Complement cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr