ENSG00000281990


Homo sapiens

Features
Gene ID: ENSG00000281990
  
Biological name :IGHV1-69-2
  
Synonyms : A0A0G2JMI3 / IGHV1-69-2 / immunoglobulin heavy variable 1-69-2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.33
Gene start: 106737110
Gene end: 106737547
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000487714
swissprot - A0A0G2JMI3
Ensembl - ENSG00000281990
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ighv1-2ENSDARG00000096350Danio rerio
 ighv2-1ENSDARG00000096406Danio rerio
 ighv2-2ENSDARG00000096424Danio rerio
 ighv2-3ENSDARG00000096376Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGHV1-24 / A0A0C4DH33 / immunoglobulin heavy variable 1-24ENSG0000021195088
P23083 / IGHV1-2 / immunoglobulin heavy variable 1-2ENSG0000021193477
IGHV1-3 / A0A0C4DH29 / immunoglobulin heavy variable 1-3ENSG0000021193577
IGHV1OR15-1 / immunoglobulin heavy variable 1/OR15-1 (non-functional)ENSG0000027050576
AC135068.8ENSG0000028117976
P01743 / IGHV1-46 / immunoglobulin heavy variable 1-46ENSG0000021196275
IGHV1OR15-9 / immunoglobulin heavy variable 1/OR15-9 (non-functional)ENSG0000018840374
IGHV1-18 / A0A0C4DH31 / immunoglobulin heavy variable 1-18ENSG0000021194574
P01742 / IGHV1-69 / immunoglobulin heavy variable 1-69ENSG0000021197373
IGHV1-69D / A0A0B4J2H0 / immunoglobulin heavy variable 1-69DENSG0000028041173
IGHV1OR21-1 / immunoglobulin heavy variable 1/OR21-1 (non-functional)ENSG0000027728272
IGHV1-45 / A0A0A0MS14 / immunoglobulin heavy variable 1-45ENSG0000021196170
IGHV1-58 / A0A0C4DH39 / immunoglobulin heavy variable 1-58ENSG0000021196868
IGHV7-4-1 / A0A0J9YVY3 / immunoglobulin heavy variable 7-4-1ENSG0000028212265
IGHV7-81 / immunoglobulin heavy variable 7-81 (non-functional)ENSG0000021197962
IGHV5-51 / A0A0C4DH38 / immunoglobulin heavy variable 5-51ENSG0000021196661
A0A0J9YXX1 / IGHV5-10-1 / immunoglobulin heavy variable 5-10-1ENSG0000028265161


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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