Manteia

ENSG00000211973

Homo sapiens

Features

Gene ID:	ENSG00000211973

Biological name :	IGHV1-69

Synonyms :	IGHV1-69 / immunoglobulin heavy variable 1-69 / P01742

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	14
Strand:	-1
Band:	q32.33
Gene start:	106714684
Gene end:	106715181

Corresponding Affymetrix probe sets:	211634_x_at (Human Genome U133 Plus 2.0 Array) 211635_x_at (Human Genome U133 Plus 2.0 Array) 240915_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000375042 swissprot - P01742 Ensembl - ENSG00000211973

See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
IGHV1-69D / A0A0B4J2H0 / immunoglobulin heavy variable 1-69D	ENSG00000280411	99
IGHV1-3 / A0A0C4DH29 / immunoglobulin heavy variable 1-3	ENSG00000211935	81
IGHV1-18 / A0A0C4DH31 / immunoglobulin heavy variable 1-18	ENSG00000211945	81
P23083 / IGHV1-2 / immunoglobulin heavy variable 1-2	ENSG00000211934	79
P01743 / IGHV1-46 / immunoglobulin heavy variable 1-46	ENSG00000211962	78
IGHV1OR15-1 / immunoglobulin heavy variable 1/OR15-1 (non-functional)	ENSG00000270505	78
AC135068.8	ENSG00000281179	78
IGHV1-45 / A0A0A0MS14 / immunoglobulin heavy variable 1-45	ENSG00000211961	77
IGHV1-58 / A0A0C4DH39 / immunoglobulin heavy variable 1-58	ENSG00000211968	76
IGHV1-24 / A0A0C4DH33 / immunoglobulin heavy variable 1-24	ENSG00000211950	75
IGHV1OR21-1 / immunoglobulin heavy variable 1/OR21-1 (non-functional)	ENSG00000277282	73
A0A0G2JMI3 / IGHV1-69-2 / immunoglobulin heavy variable 1-69-2	ENSG00000281990	73
IGHV1OR15-9 / immunoglobulin heavy variable 1/OR15-9 (non-functional)	ENSG00000188403	72
IGHV7-4-1 / A0A0J9YVY3 / immunoglobulin heavy variable 7-4-1	ENSG00000282122	71
IGHV7-81 / immunoglobulin heavy variable 7-81 (non-functional)	ENSG00000211979	65
A0A0J9YXX1 / IGHV5-10-1 / immunoglobulin heavy variable 5-10-1	ENSG00000282651	61
IGHV5-51 / A0A0C4DH38 / immunoglobulin heavy variable 5-51	ENSG00000211966	60

Protein motifs (from Interpro)

Interpro ID

Name

No match

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002250	adaptive immune response	IEA
biological_process	GO:0002376	immune system process	IEA
biological_process	GO:0006508	proteolysis	IEA
biological_process	GO:0006898	receptor-mediated endocytosis	TAS
biological_process	GO:0006955	immune response	NAS
biological_process	GO:0006956	complement activation	TAS
biological_process	GO:0006958	complement activation, classical pathway	TAS
biological_process	GO:0030449	regulation of complement activation	TAS
biological_process	GO:0038095	Fc-epsilon receptor signaling pathway	TAS
biological_process	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	TAS
biological_process	GO:0050776	regulation of immune response	TAS
biological_process	GO:0050900	leukocyte migration	TAS
cellular_component	GO:0005576	extracellular region	TAS
cellular_component	GO:0005886	plasma membrane	TAS
cellular_component	GO:0016020	membrane	IEA
molecular_function	GO:0003823	antigen binding	NAS
molecular_function	GO:0004252	serine-type endopeptidase activity	TAS

Pathways (from Reactome)

Pathway description

Initial triggering of complement

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr