ENSDARG00000001807


Danio rerio

Features
Gene ID: ENSDARG00000001807
  
Biological name :tnfrsf21
  
Synonyms : tnfrsf21 / tumor necrosis factor receptor superfamily, member 21
  
Possible biological names infered from orthology : O75509 / Q9EPU5 / TNF receptor superfamily member 21
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 35797998
Gene end: 35841570
  
Corresponding Affymetrix probe sets: Dr.964.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000036002
swissprot - Q5TYN2
ZFIN ID - ZDB-GENE-030131-5971
Ensembl - ENSDARG00000001807
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNFRSF21ENSGALG00000016719Gallus gallus
 O75509ENSG00000146072Homo sapiens
 Q9EPU5ENSMUSG00000023915Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnfrsf1b / tumor necrosis factor receptor superfamily, member 1B / P20333* / P25119* / TNF receptor superfamily member 1B*ENSDARG0000007016513
tnfrsf11a / tumor necrosis factor receptor superfamily, member 11a, NFKB activator / CD40* / Q9Y6Q6* / O35305* / P25942* / P27512* / CD40 molecule* / TNF receptor superfamily member 11a* / ...ENSDARG0000008780412
tnfrsf11b / tumor necrosis factor receptor superfamily, member 11b / O95407* / O00300* / O08712* / TNFRSF6B* / TNF receptor superfamily member 6b* / TNF receptor superfamily member 11b* / t...ENSDARG000000983779
zgc:153631 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000689938
si:dkey-23c22.7 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000951938
si:dkey-23c22.5 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000928928
zgc:153759 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000689698
zgc:153759 / si:dkey-23c22.9 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000923818
si:ch211-261n11.8 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000899018
cd40 / CD40 molecule, TNF receptor superfamily member 5 / P27512* / O35305* / P25942* / Q9Y6Q6* / TNFRSF11A* / CD40 molecule* / TNF receptor superfamily member 11a* / Tumor necrosis factor ...ENSDARG000000549688
si:ch211-261n11.7 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000689668
CT737125.1 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG000000689917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR011029  Death-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR022330  Tumour necrosis factor receptor 21
 IPR034034  Tumor necrosis factor receptor 21, N-terminal
 IPR034037  Tumor necrosis factor receptor 21, death domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0014045 establishment of endothelial blood-brain barrier IMP
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000099 brain vasculature brain vasculature increased permeability , abnormal
brain vasculature has fewer parts of type central artery , abnormal
Show

 ZFA:0005020 central artery central artery malformed , abnormal
central artery decreased branchiness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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