ENSDARG00000002909


Danio rerio

Features
Gene ID: ENSDARG00000002909
  
Biological name :tjp3
  
Synonyms : tight junction protein 3 / tjp3
  
Possible biological names infered from orthology : O95049
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 17657612
Gene end: 17688873
  
Corresponding Affymetrix probe sets: Dr.21038.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000116937
Ensembl peptide - ENSDARP00000120369
Ensembl peptide - ENSDARP00000117808
Ensembl peptide - ENSDARP00000025259
NCBI entrez gene - 373089     See in Manteia.
RefSeq - NM_001328340
RefSeq - XM_005170442
RefSeq Peptide - NP_001315269
swissprot - F1R3X0
swissprot - E9QHG6
swissprot - E9QGL7
swissprot - F1QXZ7
ZFIN ID - ZDB-GENE-030828-10
Ensembl - ENSDARG00000002909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TJP3ENSGALG00000000748Gallus gallus
 TJP3ENSG00000105289Homo sapiens
 Tjp3ENSMUSG00000034917Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tjp1a / tight junction protein 1a / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007750631
tjp2b / tight junction protein 2b (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000002344330
tjp1b / tight junction protein 1b / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007937430
tjp2a / tight junction protein 2a (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000006330930
dlg5a / discs, large homolog 5a (Drosophila) / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000007405915
dlg5b.1 / discs, large homolog 5b (Drosophila), tandem duplicate 1 / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000009094913
dlg1 / Q5PYH6 / discs, large homolog 1 (Drosophila) / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000000967711
dlg2 / discs, large homolog 2 (Drosophila) / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSDARG0000009932311
dlg1l / Q5PYH5 / discs, large (Drosophila) homolog 1, like / DLG1* / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000010221611
dlg3 / discs, large homolog 3 (Drosophila) / P70175* / Q92796* / Disks large homolog 3 * / discs large MAGUK scaffold protein 3*ENSDARG0000007679611
dlg4a / discs, large homolog 4a (Drosophila) / DLG4* / P78352* / discs large MAGUK scaffold protein 4*ENSDARG0000004192610
mpp5a / membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG000000062728
mpp3b / membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG000000626678
dlg4b / discs, large homolog 4b (Drosophila)ENSDARG000000393858
mpp3a / membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG000000151848
caska / calcium/calmodulin-dependent serine protein kinase a / CASK* / O70589* / O14936* / Peripheral plasma membrane protein CASK * / calcium/calmodulin dependent serine protein kinase*ENSDARG000000598097
mpp7a / Q6P0D7 / membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) / MPP7* / Q5T2T1* / membrane palmitoylated protein 7* / MAGUK p55 subfamily member 7 isoform 2 *ENSDARG000001024707
mpp5b / membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG000000047217
mpp4a / membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4) / MPP4* / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 * / membrane palmitoylated protein 4*ENSDARG000000582227
mpp6b / membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG000000297617


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR005420  Tight junction protein ZO-3
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030104 water homeostasis IMP
 biological_processGO:0048871 multicellular organismal homeostasis IMP
 cellular_componentGO:0005923 bicellular tight junction IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000086 EVL EVL lacks parts or has fewer parts of type EVL bicellular tight junction, abnormal
EVL bicellular tight junction decreased amount , abnormal
EVL increased permeability , abnormal
Show

 ZFA:0000094 blood island blood island increased size , abnormal
Show

 ZFA:0001058 caudal fin caudal fin decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region increased curvature , abnormal
post-vent region structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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