ENSDARG00000077506


Danio rerio

Features
Gene ID: ENSDARG00000077506
  
Biological name :tjp1a
  
Synonyms : tight junction protein 1a / tjp1a
  
Possible biological names infered from orthology : P39447 / Q07157 / tight junction protein 1 / TJP1
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 30930653
Gene end: 31142273
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129419
Ensembl peptide - ENSDARP00000156719
Ensembl peptide - ENSDARP00000148362
Ensembl peptide - ENSDARP00000142980
Ensembl peptide - ENSDARP00000142856
Ensembl peptide - ENSDARP00000142806
Ensembl peptide - ENSDARP00000142798
Ensembl peptide - ENSDARP00000142670
Ensembl peptide - ENSDARP00000099537
Ensembl peptide - ENSDARP00000114645
Ensembl peptide - ENSDARP00000129185
NCBI entrez gene - 378845     See in Manteia.
RefSeq - XM_009303258
swissprot - E7F2W2
swissprot - A0A1D5NT08
swissprot - A0A1D5NSN9
swissprot - A0A1D5NSJ0
swissprot - A0A1D5NSI3
swissprot - A0A1D5NS61
swissprot - X1WG30
swissprot - X1WGR1
swissprot - E9QET4
ZFIN ID - ZDB-GENE-031001-2
Ensembl - ENSDARG00000077506
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TJP1ENSGALG00000042552Gallus gallus
 TJP1ENSG00000104067Homo sapiens
 Tjp1ENSMUSG00000030516Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tjp1b / tight junction protein 1b / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007937472
tjp2b / tight junction protein 2b (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000002344331
tjp2a / tight junction protein 2a (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000006330930
tjp3 / tight junction protein 3 / O95049*ENSDARG0000000290923
dlg5a / discs, large homolog 5a (Drosophila) / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000007405912
dlg5b.1 / discs, large homolog 5b (Drosophila), tandem duplicate 1 / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000009094911
dlg1 / Q5PYH6 / discs, large homolog 1 (Drosophila) / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000000967710
dlg2 / discs, large homolog 2 (Drosophila) / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSDARG0000009932310
dlg4a / discs, large homolog 4a (Drosophila) / DLG4* / P78352* / discs large MAGUK scaffold protein 4*ENSDARG000000419269
dlg3 / discs, large homolog 3 (Drosophila) / P70175* / Q92796* / Disks large homolog 3 * / discs large MAGUK scaffold protein 3*ENSDARG000000767969
dlg1l / Q5PYH5 / discs, large (Drosophila) homolog 1, like / DLG1* / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG000001022169
mpp3a / membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG000000151847
mpp5a / membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG000000062727
mpp7a / Q6P0D7 / membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) / MPP7* / Q5T2T1* / membrane palmitoylated protein 7* / MAGUK p55 subfamily member 7 isoform 2 *ENSDARG000001024707
caska / calcium/calmodulin-dependent serine protein kinase a / CASK* / O70589* / O14936* / Peripheral plasma membrane protein CASK * / calcium/calmodulin dependent serine protein kinase*ENSDARG000000598097
dlg4b / discs, large homolog 4b (Drosophila)ENSDARG000000393856
mpp3b / membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG000000626676
mpp4a / membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4) / MPP4* / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 * / membrane palmitoylated protein 4*ENSDARG000000582226
mpp6a / membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG000000568926
mpp5b / membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG000000047216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000906  ZU5 domain
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR005417  Tight junction protein ZO
 IPR005418  Tight junction protein ZO-1
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035597  ZO-1, SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043473 pigmentation IMP
 cellular_componentGO:0005923 bicellular tight junction IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
c-src mediated regulation of Cx43 function and closure of gap junctions
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001463 melanophore stripe melanophore stripe undulate , abnormal
melanophore stripe broken , abnormal
Show

 ZFA:0009091 melanocyte melanocyte morphology , abnormal
melanocyte decreased amount , abnormal
Show

 ZFA:0009198 xanthophore xanthophore displaced to melanophore stripe , abnormal
Show

 ZFA:0009199 iridophore iridophore pigmentation process quality , abnormal
iridophore displaced to melanophore stripe , abnormal
iridophore absent , abnormal
iridophore structure , abnormal
iridophore behavioral quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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