ENSDARG00000041926


Danio rerio

Features
Gene ID: ENSDARG00000041926
  
Biological name :dlg4a
  
Synonyms : discs, large homolog 4a (Drosophila) / dlg4a
  
Possible biological names infered from orthology : discs large MAGUK scaffold protein 4 / Disks large homolog 4 / DLG4 / P78352 / Q62108
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 68529728
Gene end: 68641353
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000048431
swissprot - F1QCS0
ZFIN ID - ZDB-GENE-130530-613
Ensembl - ENSDARG00000041926
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DLG4ENSG00000132535Homo sapiens
 Dlg4ENSMUSG00000020886Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlg1 / Q5PYH6 / discs, large homolog 1 (Drosophila) / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000000967771
dlg1l / Q5PYH5 / discs, large (Drosophila) homolog 1, like / DLG1* / Q12959* / Q811D0* / Disks large homolog 1 * / discs large MAGUK scaffold protein 1*ENSDARG0000010221669
dlg2 / discs, large homolog 2 (Drosophila) / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSDARG0000009932368
dlg3 / discs, large homolog 3 (Drosophila) / P70175* / Q92796* / Disks large homolog 3 * / discs large MAGUK scaffold protein 3*ENSDARG0000007679662
dlg4b / discs, large homolog 4b (Drosophila)ENSDARG0000003938552
dlg5a / discs, large homolog 5a (Drosophila) / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000007405923
dlg5b.1 / discs, large homolog 5b (Drosophila), tandem duplicate 1 / DLG5* / E9Q9R9* / Q8TDM6* / Disks large homolog 5 * / discs large MAGUK scaffold protein 5*ENSDARG0000009094922
tjp1a / tight junction protein 1a / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007750621
tjp1b / tight junction protein 1b / TJP1* / P39447* / Q07157* / tight junction protein 1*ENSDARG0000007937420
tjp2b / tight junction protein 2b (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000002344320
tjp3 / tight junction protein 3 / O95049*ENSDARG0000000290919
tjp2a / tight junction protein 2a (zona occludens 2) / TJP2* / Q9UDY2* / Q9Z0U1* / AL358113.1* / tight junction protein 2* / Tight junction protein ZO-2 *ENSDARG0000006330919
mpp5a / membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG0000000627219
mpp6b / membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG0000002976118
mpp3b / membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG0000006266718
mpp2a / membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2) / MPP2* / Q14168* / Q9WV34* / membrane palmitoylated protein 2* / Mus musculus membrane protein, palmitoylated 2 (M...ENSDARG0000005345318
mpp5b / membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5) / MPP5* / Q8N3R9* / Q9JLB2* / membrane palmitoylated protein 5* / membrane protein, palmitoylated 5 (MAGUK p55 subf...ENSDARG0000000472118
mpp7a / Q6P0D7 / membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) / MPP7* / Q5T2T1* / membrane palmitoylated protein 7* / MAGUK p55 subfamily member 7 isoform 2 *ENSDARG0000010247018
mpp6a / membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6) / MPP6* / Q9JLB0* / Q9NZW5* / membrane palmitoylated protein 6* / membrane protein, palmitoylated 6 (MAGUK p55 subf...ENSDARG0000005689218
mpp3a / membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3) / MPP3* / Q13368* / membrane palmitoylated protein 3*ENSDARG0000001518418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR016313  Disks large 1-like
 IPR019583  PDZ-associated domain of NMDA receptors
 IPR019590  Disks large homologue 1, N-terminal PEST domain
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
Activation of Ca-permeable Kainate Receptor
RHO GTPases activate CIT
RAF/MAP kinase cascade
Neurexins and neuroligins
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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