ENSMUSG00000034917


Mus musculus

Features
Gene ID: ENSMUSG00000034917
  
Biological name :Tjp3
  
Synonyms : tight junction protein 3 / Tjp3
  
Possible biological names infered from orthology : O95049
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 81273207
Gene end: 81291581
  
Corresponding Affymetrix probe sets: 10371111 (MoGene1.0st)   1417896_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036438
Ensembl peptide - ENSMUSP00000151601
Ensembl peptide - ENSMUSP00000151819
NCBI entrez gene - 27375     See in Manteia.
MGI - MGI:1351650
RefSeq - XM_006513708
RefSeq - NM_001282095
RefSeq - NM_001282096
RefSeq - NM_013769
RefSeq Peptide - NP_001269024
RefSeq Peptide - NP_001269025
RefSeq Peptide - NP_038797
swissprot - Q921G9
swissprot - A0A1W2P7W7
Ensembl - ENSMUSG00000034917
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tjp3ENSDARG00000002909Danio rerio
 TJP3ENSGALG00000000748Gallus gallus
 TJP3ENSG00000105289Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051643
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481243
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178220
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257219
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088618
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088118
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277018
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744014
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237313
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731411
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101211
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955011
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111211
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838810
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG000000314029
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG000000204444


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR005417  Tight junction protein ZO
 IPR005420  Tight junction protein ZO-3
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abca4tm1Ght/Abca4tm1Ght
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Tjp3tm1Whun/Tjp3tm1Whun
Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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