ENSMUSG00000021112


Mus musculus

Features
Gene ID: ENSMUSG00000021112
  
Biological name :Mpp5
  
Synonyms : membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Mpp5 / Q9JLB2
  
Possible biological names infered from orthology : membrane palmitoylated protein 5 / Q8N3R9
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C3
Gene start: 78748907
Gene end: 78840714
  
Corresponding Affymetrix probe sets: 10396778 (MoGene1.0st)   1421064_at (Mouse Genome 430 2.0 Array)   1434954_at (Mouse Genome 430 2.0 Array)   1450113_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080683
Ensembl peptide - ENSMUSP00000151872
Ensembl peptide - ENSMUSP00000151349
NCBI entrez gene - 56217     See in Manteia.
MGI - MGI:1927339
RefSeq - XM_006516097
RefSeq - XM_017315139
RefSeq - XM_006516098
RefSeq - NM_019579
RefSeq Peptide - NP_062525
swissprot - Q9JLB2
swissprot - B2RRY4
swissprot - A0A1W2P6P0
swissprot - A0A1W2P7Z6
Ensembl - ENSMUSG00000021112
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp5aENSDARG00000006272Danio rerio
 mpp5bENSDARG00000004721Danio rerio
 MPP5ENSGALG00000009581Gallus gallus
 MPP5ENSG00000072415Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744031
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955029
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237328
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731427
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838827
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088125
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257225
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101225
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277024
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088622
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140220
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178217
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051616
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481216
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491715
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR015145  L27-N
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031185  MAGUK p55 subfamily member 5
 IPR035601  MPP5, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002011 morphogenesis of an epithelial sheet ISO
 biological_processGO:0007009 plasma membrane organization IMP
 biological_processGO:0032287 peripheral nervous system myelin maintenance IMP
 biological_processGO:0032288 myelin assembly IEA
 biological_processGO:0035750 protein localization to myelin sheath abaxonal region IMP
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046710 GDP metabolic process IEA
 biological_processGO:0070830 bicellular tight junction assembly IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035749 myelin sheath adaxonal region IDA
 cellular_componentGO:0043219 lateral loop IDA
 cellular_componentGO:0043220 Schmidt-Lanterman incisure IDA
 molecular_functionGO:0004385 guanylate kinase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000350 abnormal cell proliferation "anomalous growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mpp5tm1Caw/Mpp5+,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0001004 abnormal photoreceptor morphology "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001005 abnormal rod morphology "structural or developmental anomaly of the photoreceptors that contain rhodopsin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Mpp5tm1Caw/Mpp5+,Tg(rx3-icre)1Mjam/0
Genetic Background: Not Specified

 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001401 jumpy "marked by fitful, jerky movements" [J:22295]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001511 disheveled coat "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0001526 abnormal placing response "altered ability to stretch and lift the forelimbs and head to grab a close edge " [J:66943, MGI:cml]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0003241 loss of cortex neurons "loss of neurons in the cortex region of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0003354 astrocytosis "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003424 premature neuronal precursor differentiation "earlier than normal transformation of neuronal precursor cells into neurons" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mpp5tm1Caw/Mpp5+,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003731 abnormal outer nuclear layer morphology "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003734 abnormal inner plexiform layer morphology "malformation/anomalous structure of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5+,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0004948 abnormal neuronal precursor proliferation "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Mpp5tm1Caw/Mpp5+,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0005424 jerky movement "continuous, abrupt, faltering motions of the whole body or a portion of the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0006254 thin cerebral cortex "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0008067 retinal ganglion cell degeneration "degeneration or loss of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008283 small hippocampus "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5+,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0008450 retinal photoreceptor degeneration "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008507 thin retinal ganglion layer "reduced thickness of the innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008509 disorganized retinal ganglion layer "derangement of the pattern of the innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008513 thin retinal inner plexiform layer "reduced thickness of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008516 disorganized retinal outer nuclear layer "derangement of the normal pattern of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008518 retinal outer nuclear layer degeneration "a retrogressive impairment or destruction of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008582 short photoreceptor inner segment "decreased length of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008583 absent photoreceptor inner segment "absence of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008585 absent photoreceptor outer segment "absence of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008587 short photoreceptor outer segment "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008918 microgliosis "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S2/SvPas

 MP:0010236 abnormal retina outer limiting membrane morphology "any structural anomaly of the row of junctional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

 MP:0030005 increased retinal apoptosis "increase in the number of cells in the retina undergoing programmed cell death" [MGI:anna]
Show

Allelic Composition: Oca2p-86H/Oca2p
Genetic Background: involves: 101/H * C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000044279 Crb3 / Q8QZT4 / Mus musculus crumbs family member 3 (Crb3), transcript variant 2, mRNA. / Q9BUF7* / crumbs 3, cell polarity complex component*  / reaction / complex
 ENSMUSG00000061859 Patj / Q63ZW7 / Mus musculus PATJ, crumbs cell polarity complex component (Patj), transcript variant 5, mRNA. / Q8NI35* / PATJ, crumbs cell polarity complex component*  / complex / reaction






 

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