ENSMUSG00000017314


Mus musculus

Features
Gene ID: ENSMUSG00000017314
  
Biological name :Mpp2
  
Synonyms : Mpp2 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q9WV34
  
Possible biological names infered from orthology : membrane palmitoylated protein 2 / Q14168
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 102057015
Gene end: 102088515
  
Corresponding Affymetrix probe sets: 10391540 (MoGene1.0st)   1449173_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017458
Ensembl peptide - ENSMUSP00000097967
NCBI entrez gene - 50997     See in Manteia.
MGI - MGI:1858257
RefSeq - XM_006533687
RefSeq - NM_001356324
RefSeq - NM_016695
RefSeq - XM_006533683
RefSeq - XM_006533684
RefSeq - XM_006533685
RefSeq Peptide - NP_057904
RefSeq Peptide - NP_001343253
swissprot - Q9WV34
Ensembl - ENSMUSG00000017314
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp2aENSDARG00000053453Danio rerio
 mpp2bENSDARG00000010957Danio rerio
 MPP2ENSGALG00000035580Gallus gallus
 MPP2ENSG00000108852Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838867
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101242
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744037
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140234
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111233
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237333
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955031
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257227
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088127
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277027
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088626
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481220
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051619
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178218
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491718
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035602  MPP2, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051260 protein homooligomerization ISS
 biological_processGO:0060079 excitatory postsynaptic potential IMP
 biological_processGO:0060291 long-term synaptic potentiation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032590 dendrite membrane IDA
 cellular_componentGO:0032591 dendritic spine membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IDA
 cellular_componentGO:0043198 dendritic shaft IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0044325 ion channel binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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