ENSMUSG00000057440


Mus musculus

Features
Gene ID: ENSMUSG00000057440
  
Biological name :Mpp7
  
Synonyms : MAGUK p55 subfamily member 7 isoform 2 / Mpp7
  
Possible biological names infered from orthology : membrane palmitoylated protein 7 / Q5T2T1
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: A1
Gene start: 7347962
Gene end: 7626863
  
Corresponding Affymetrix probe sets: 10457357 (MoGene1.0st)   10457359 (MoGene1.0st)   1432216_s_at (Mouse Genome 430 2.0 Array)   1443971_x_at (Mouse Genome 430 2.0 Array)   1453690_at (Mouse Genome 430 2.0 Array)   1454158_at (Mouse Genome 430 2.0 Array)   1455179_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111535
NCBI entrez gene - 75739     See in Manteia.
MGI - MGI:1922989
RefSeq - XM_017318009
RefSeq - NM_001081287
RefSeq - NM_001161620
RefSeq - XM_011247027
RefSeq - XM_017318006
RefSeq - XM_017318007
RefSeq - XM_006526325
RefSeq - XM_006526326
RefSeq - XM_006526327
RefSeq - XM_011247025
RefSeq - XM_011247026
RefSeq Peptide - NP_001074756
RefSeq Peptide - NP_001155092
swissprot - G5E8S8
Ensembl - ENSMUSG00000057440
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp7aENSDARG00000102470Danio rerio
 MPP7ENSGALG00000007408Gallus gallus
 MPP7ENSG00000150054Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237354
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955042
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111237
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731435
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838834
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101232
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088128
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140227
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257227
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277026
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088626
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178223
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491721
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051620
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481220
Guk1 / guanylate kinase 1 / Q16774*ENSMUSG0000002044414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035599  MPP7, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031334 positive regulation of protein complex assembly IEA
 biological_processGO:0070830 bicellular tight junction assembly IEA
 biological_processGO:0071896 protein localization to adherens junction IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0097025 MPP7-DLG1-LIN7 complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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