ENSG00000150054


Homo sapiens

Features
Gene ID: ENSG00000150054
  
Biological name :MPP7
  
Synonyms : membrane palmitoylated protein 7 / MPP7 / Q5T2T1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p12.1
Gene start: 28050993
Gene end: 28334486
  
Corresponding Affymetrix probe sets: 1564308_a_at (Human Genome U133 Plus 2.0 Array)   237495_at (Human Genome U133 Plus 2.0 Array)   238451_at (Human Genome U133 Plus 2.0 Array)   238778_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364871
Ensembl peptide - ENSP00000337907
Ensembl peptide - ENSP00000398319
Ensembl peptide - ENSP00000473899
Ensembl peptide - ENSP00000364884
NCBI entrez gene - 143098     See in Manteia.
OMIM - 610973
RefSeq - XM_017015742
RefSeq - NM_001318170
RefSeq - NM_173496
RefSeq - XM_011519337
RefSeq - XM_011519338
RefSeq - XM_017015741
RefSeq Peptide - NP_001305099
RefSeq Peptide - NP_775767
swissprot - U5GXS2
swissprot - Q5T2T1
swissprot - S4R337
Ensembl - ENSG00000150054
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mpp7aENSDARG00000102470Danio rerio
 MPP7ENSGALG00000007408Gallus gallus
 Mpp7ENSMUSG00000057440Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MPP3 / Q13368 / membrane palmitoylated protein 3ENSG0000016164756
MPP4 / Q96JB8 / membrane palmitoylated protein 4ENSG0000008212642
MPP5 / Q8N3R9 / membrane palmitoylated protein 5ENSG0000007241537
MPP6 / Q9NZW5 / membrane palmitoylated protein 6ENSG0000010592635
MPP2 / Q14168 / membrane palmitoylated protein 2ENSG0000010885235
CASK / O14936 / calcium/calmodulin dependent serine protein kinaseENSG0000014704431
DLG3 / Q92796 / discs large MAGUK scaffold protein 3ENSG0000008245828
MPP1 / Q00013 / membrane palmitoylated protein 1ENSG0000013083028
DLG2 / Q15700 / discs large MAGUK scaffold protein 2ENSG0000015067227
DLG1 / Q12959 / discs large MAGUK scaffold protein 1ENSG0000007571127
DLG4 / P78352 / discs large MAGUK scaffold protein 4ENSG0000013253525
DLG5 / Q8TDM6 / discs large MAGUK scaffold protein 5ENSG0000015120823
TJP2 / Q9UDY2 / tight junction protein 2ENSG0000011913921
TJP3 / O95049 / tight junction protein 3ENSG0000010528921
AL358113.1ENSG0000028513021
TJP1 / Q07157 / tight junction protein 1ENSG0000010406720
GUK1 / Q16774 / guanylate kinase 1ENSG0000014377412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035599  MPP7, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0030010 establishment of cell polarity TAS
 biological_processGO:0031334 positive regulation of protein complex assembly TAS
 biological_processGO:0070830 bicellular tight junction assembly IDA
 biological_processGO:0071896 protein localization to adherens junction IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005912 adherens junction IDA
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0097025 MPP7-DLG1-LIN7 complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0032947 protein-containing complex scaffold activity IDA
 molecular_functionGO:0035591 signaling adaptor activity TAS
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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