ENSMUSG00000020444


Mus musculus

Features
Gene ID: ENSMUSG00000020444
  
Biological name :Guk1
  
Synonyms : guanylate kinase 1 / Guk1
  
Possible biological names infered from orthology : Q16774
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 59183875
Gene end: 59192212
  
Corresponding Affymetrix probe sets: 10386359 (MoGene1.0st)   1416395_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127566
Ensembl peptide - ENSMUSP00000130214
Ensembl peptide - ENSMUSP00000134236
NCBI entrez gene - 14923     See in Manteia.
MGI - MGI:95871
RefSeq - XM_006532246
RefSeq - NM_001159410
RefSeq - NM_008193
RefSeq - XM_006532245
RefSeq Peptide - NP_001152882
RefSeq Peptide - NP_032219
swissprot - G3UYV3
swissprot - Q564G0
swissprot - E9Q7K1
Ensembl - ENSMUSG00000020444
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 guk1aENSDARG00000030340Danio rerio
 guk1bENSDARG00000005776Danio rerio
 GUK1ENSGALG00000005336Gallus gallus
 GUK1ENSG00000143774Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mpp4 / Q6P7F1 / MAGUK p55 subfamily member 4 / Q96JB8* / membrane palmitoylated protein 4*ENSMUSG0000007955037
Mpp7 / MAGUK p55 subfamily member 7 isoform 2 / Q5T2T1* / membrane palmitoylated protein 7*ENSMUSG0000005744037
Mpp5 / Q9JLB2 / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) / Q8N3R9* / membrane palmitoylated protein 5*ENSMUSG0000002111236
Mpp6 / Q9JLB0 / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) / Q9NZW5* / membrane palmitoylated protein 6*ENSMUSG0000003838833
Mpp2 / Q9WV34 / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA. / Q14168* / membrane palmitoylated protein 2*ENSMUSG0000001731432
Dlg1 / Q811D0 / Disks large homolog 1 / Q12959* / discs large MAGUK scaffold protein 1*ENSMUSG0000002277032
Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*ENSMUSG0000002088632
Dlg3 / P70175 / Disks large homolog 3 / Q92796* / discs large MAGUK scaffold protein 3*ENSMUSG0000000088132
Mpp3 / membrane palmitoylated protein 3 / Q13368*ENSMUSG0000005237331
Dlg2 / Q91XM9 / Disks large homolog 2 / Q15700* / discs large MAGUK scaffold protein 2*ENSMUSG0000005257231
Mpp1 / P70290 / membrane protein, palmitoylated / Q00013* / membrane palmitoylated protein 1*ENSMUSG0000003140226
Cask / O70589 / Peripheral plasma membrane protein CASK / O14936* / calcium/calmodulin dependent serine protein kinase*ENSMUSG0000003101226
Tjp2 / Q9Z0U1 / Tight junction protein ZO-2 / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSMUSG0000002481218
Tjp1 / P39447 / tight junction protein 1 / Q07157*ENSMUSG0000003051618
Dlg5 / E9Q9R9 / Disks large homolog 5 / Q8TDM6* / discs large MAGUK scaffold protein 5*ENSMUSG0000002178217
Tjp3 / tight junction protein 3 / O95049*ENSMUSG0000003491716


Protein motifs (from Interpro)
Interpro ID Name
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR017665  Guanylate kinase
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006163 purine nucleotide metabolic process IEA
 biological_processGO:0006185 dGDP biosynthetic process IEA
 biological_processGO:0019673 GDP-mannose metabolic process IEA
 biological_processGO:0034436 glycoprotein transport IEA
 biological_processGO:0046034 ATP metabolic process IEA
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046054 dGMP metabolic process IEA
 biological_processGO:0046060 dATP metabolic process IEA
 biological_processGO:0046710 GDP metabolic process IEA
 biological_processGO:0046711 GDP biosynthetic process IEA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004385 guanylate kinase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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